Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1255885 | 0.80 | MEN1 (0.56) | KMT2AMEN1NOTUMAPOBEC3GALDH1A1 | |
| SCHEMBL6163681 | 0.78 | MEN1 (0.44) | KMT2AMEN1NOTUMAPOBEC3GALDH1A1 | |
| SCHEMBL11706244 | 0.78 | SLC2A1 (0.46) | KMT2AMEN1NOTUMJAK2JAK1 | |
| SCHEMBL28872504 | 0.74 | KMT2A (0.38) | KMT2AMEN1NOTUMJAK2JAK1 | |
| SCHEMBL205408 | 0.74 | CA1 (0.48) | KMT2AMEN1ALDH1A1TSHRCA12 | |
| SCHEMBL31701218 | 0.74 | MAPT (0.46) | KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL2896727 | 0.74 | ALDH1A1 (0.47) | KMT2AMEN1JAK2JAK1TYK2 | |
| SCHEMBL13729839 | 0.74 | HDAC8 (0.47) | JAK2JAK1TYK2APOBEC3GTSHR | |
| SCHEMBL26336607 | 0.74 | APOBEC3G (0.46) | KMT2AMEN1NOTUMJAK2JAK1 | |
| SCHEMBL26350804 | 0.74 | APOBEC3G (0.46) | KMT2AMEN1NOTUMJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989625-B2 | Thienopyridines | MERCK PATENT GMBH (DE) | 2011-08-02 | — | — | US | disclosed |
| US-20100048558-A1 | THIENOPYRIDINES | MERCK PATENT GESELLSCHAFT (DE) | 2010-02-25 | — | — | US | disclosed |
| CN-101163707-A | Thienopyridines | MERCK PATENT GMBH (DE) | 2008-04-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048558-A1 | THIENOPYRIDINES | HSP90AB2P, HSP90AB1, HSP90AA1 | KMT2A 3874/4885MEN1 4504/4885NOTUM 4669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.