Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL205408 | 0.81 | CA1 (0.48) | KMT2AMEN1L3MBTL1KDM4EGAA | |
| SCHEMBL2969266 | 0.77 | CA12 (0.53) | KMT2AMEN1L3MBTL1KDM4ECA12 | |
| SCHEMBL1255885 | 0.75 | MEN1 (0.56) | KMT2AMEN1NOTUMAPOBEC3GL3MBTL1 | |
| SCHEMBL2291968 | 0.74 | KMT2A (0.41) | KMT2AMEN1NOTUMAPOBEC3GNSD2 | |
| SCHEMBL6163681 | 0.74 | MEN1 (0.44) | KMT2AMEN1NOTUMAPOBEC3GL3MBTL1 | |
| SCHEMBL11706244 | 0.74 | SLC2A1 (0.46) | KMT2AMEN1NOTUMAPOBEC3GJAK2 | |
| SCHEMBL23397120 | 0.72 | TDP1 (0.60) | KMT2ANSD2ABL1PPARGRIN1 | |
| SCHEMBL1116172 | 0.70 | ATM (0.46) | L3MBTL1KDM4EGAACA12CA9 | |
| SCHEMBL31701218 | 0.69 | MAPT (0.46) | KMT2AMEN1CREBBPALDH1A1HPGD | |
| SCHEMBL2896727 | 0.69 | ALDH1A1 (0.47) | KMT2AMEN1APOBEC3GNSD2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109562185-A | Novel conjugates of agents and moieties capable of binding to glucose-sensing proteins | 赛诺菲 | 2019-04-02 | — | — | CN | disclosed |