SCHEMBL22919915

SCHEMBL22919915

CC1C=C(c2ccccc2)C=CN1C

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.36
BRD4 O60885 1/20 0.35
CCL2 P13500 1/20 0.35
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
KMT2A Q03164 1/20 0.31
SLC22A2 O15244 1/20 0.30
SLC22A1 O15245 1/20 0.30
SLC22A3 O75751 1/20 0.30
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28029305 0.71 GABRP (0.31)
SCHEMBL23058910 0.67 ALDH1A1 (0.38) HTTKMT2A
SCHEMBL3000591 0.67 BRD4 (0.41) HTTBRD4CCL2CYP1A2CYP3A4
SCHEMBL23058912 0.67 ALDH1A1 (0.38) HTTKMT2A
SCHEMBL22275567 0.66
SCHEMBL3011281 0.63 KMT2A (0.36) KMT2ASLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL24355003 0.61 HTT (0.36) HTTCYP1A2CYP3A4CYP2D6
SCHEMBL24032433 0.61 HTT (0.36) HTT
SCHEMBL16001320 0.61 ALDH1A1 (0.40) BRD4CYP1A2CYP3A4CYP2D6KMT2A
SCHEMBL6903276 0.61 HTT (0.36) HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3770166-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2021-01-27 EP disclosed