SCHEMBL22920802

SCHEMBL22920802

CC1(C)c2ccccc2-c2c1ccc1c2-c2cc(Cl)ccc2C1(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 8/20 0.46
PGR P06401 3/20 0.43
S100A4 P26447 1/20 0.39
AKR1A1 P14550 1/20 0.36
AKR1B1 P15121 1/20 0.36
PTPN1 P18031 1/20 0.35
MLNR O43193 1/20 0.35
NR1I2 O75469 1/20 0.35
CHRM2 P08172 1/20 0.35
ADRB1 P08588 1/20 0.35
HTR1A P08908 1/20 0.35
ADRA2A P08913 1/20 0.35
CHRM1 P11229 1/20 0.35
DRD2 P14416 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
CHRM3 P20309 1/20 0.35
DRD1 P21728 1/20 0.35
SLC6A2 P23975 1/20 0.35
HTR2A P28223 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19849937 0.87 PDK2 (0.59) PDK2PGRS100A4AKR1A1AKR1B1
SCHEMBL22920723 0.85 PDK2 (0.44) PDK2PGRS100A4AKR1A1AKR1B1
SCHEMBL26602840 0.85 PGR (0.42) PDK2PGRAKR1A1AKR1B1NR1I2
SCHEMBL20806340 0.84 PDK2 (0.56) PDK2PGRS100A4AKR1A1AKR1B1
SCHEMBL25818678 0.83 PDK2 (0.35) PDK2PGR
SCHEMBL31526926 0.81 PTGES (0.39) PDK2PGR
SCHEMBL23511914 0.81 PGR (0.38) PDK2PGR
SCHEMBL22920934 0.81 PDK2 (0.43) PDK2PGRS100A4AKR1A1AKR1B1
SCHEMBL25818473 0.81 PGR (0.41) PDK2PGRS100A4AKR1A1AKR1B1
SCHEMBL24279350 0.81 PGR (0.41) PDK2PGRS100A4AKR1A1AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021015555-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2021-01-28 WO disclosed