SCHEMBL22920874

SCHEMBL22920874

CC1(C)c2ccc(Cl)cc2-c2ccc3c(c21)c1ccccc1n3-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ATM Q13315 1/20 0.40
MEN1 O00255 2/20 0.38
LMNA P02545 2/20 0.38
KMT2A Q03164 2/20 0.38
PGR P06401 1/20 0.38
MAT2A P31153 5/20 0.35
GSK3B P49841 3/20 0.34
GSK3A P49840 2/20 0.34
RGS12 O14924 1/20 0.34
GMNN O75496 1/20 0.34
USP2 O75604 1/20 0.34
CCNB2 O95067 1/20 0.34
TP53 P04637 1/20 0.34
CYP1A2 P05177 1/20 0.34
CDK1 P06493 1/20 0.34
POLB P06746 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22920741 0.92 L3MBTL1 (0.41) L3MBTL1KDM4EATMMEN1LMNA
SCHEMBL10014072 0.86 KDM4E (0.45) L3MBTL1KDM4EATMMEN1KMT2A
SCHEMBL22920878 0.86 L3MBTL1 (0.40) L3MBTL1KDM4EATMMEN1LMNA
SCHEMBL21116947 0.85 KDM4E (0.52) L3MBTL1KDM4EATMLMNAKMT2A
SCHEMBL17988890 0.84 KDM4E (0.41) L3MBTL1KDM4EATMMEN1KMT2A
SCHEMBL17245784 0.82 KDM4E (0.42) L3MBTL1KDM4EATMPGRRORC
SCHEMBL16283084 0.82 KDM4E (0.42) L3MBTL1KDM4EATMPGRRORC
SCHEMBL17245764 0.82 PGR (0.33) L3MBTL1KDM4EATMPGR
SCHEMBL17245807 0.81 KDM4E (0.39) L3MBTL1KDM4EATMPGR
SCHEMBL16283060 0.81 KDM4E (0.41) L3MBTL1KDM4EATMPGRMAT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021015555-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2021-01-28 WO disclosed