Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
| ▸ | WNT3A | P56704 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22921151 | 0.91 | TPMT (0.35) | POLBHPGDTDP1MEN1GAA | |
| SCHEMBL22921094 | 0.87 | MAPK1 (0.39) | POLBHPGDTDP1KDM4EMEN1 | |
| SCHEMBL22921161 | 0.85 | TPMT (0.31) | — | |
| SCHEMBL22921143 | 0.82 | MAPK1 (0.35) | POLBHPGDTDP1KDM4EMEN1 | |
| SCHEMBL22921097 | 0.78 | MAPK1 (0.44) | POLBHPGDTDP1KDM4EMEN1 | |
| SCHEMBL23444591 | 0.70 | PPARA (0.39) | KDM4EMEN1ALDH1A1CASP1KMT2A | |
| SCHEMBL23445208 | 0.68 | CA12 (0.43) | HPGDTDP1KDM4EALDH1A1GLA | |
| SCHEMBL22921087 | 0.66 | DRD2 (0.37) | DRD2 | |
| SCHEMBL22921085 | 0.62 | NR3C1 (0.39) | POLBKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL24003266 | 0.62 | POLB (0.46) | POLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012478-A1 | HYDROGENATION ANNULE [12] AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR | 清华大学 | 2021-01-28 | — | — | WO | disclosed |