SCHEMBL22921186

SCHEMBL22921186

CC(C)(C)C(C(=O)O)C(C)(N)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
MAPT P10636 1/20 0.36
PTGS1 P23219 1/20 0.36
TSHR P16473 1/20 0.35
SLC7A5 Q01650 1/20 0.35
GGT1 P19440 1/20 0.31
GRM2 Q14416 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6362919 1.00 ALDH1A1 (0.36) ALDH1A1MAPTPTGS1TSHRSLC7A5
SCHEMBL4553889 0.78 ALDH1A1 (0.39) ALDH1A1MAPTPTGS1TSHRSLC7A5
SCHEMBL4744014 0.76 ALDH1A1 (0.33) ALDH1A1MAPTPTGS1TSHRSLC7A5
SCHEMBL9557686 0.76 ALDH1A1 (0.33) ALDH1A1MAPTPTGS1TSHRSLC7A5
SCHEMBL4831119 0.74 ALDH1A1 (0.38) ALDH1A1MAPTPTGS1TSHRSLC7A5
SCHEMBL27665731 0.72 ALDH1A1 (0.36) ALDH1A1MAPTPTGS1TSHRSLC7A5
SCHEMBL11305045 0.72 ALDH1A1 (0.37) ALDH1A1MAPTPTGS1TSHRSLC7A5
SCHEMBL28649428 0.72 ALDH1A1 (0.54) ALDH1A1MAPTPTGS1TSHRSLC7A5
SCHEMBL723877 0.70 CYP2D6 (0.41) ALDH1A1MAPTPTGS1TSHRSLC7A5
SCHEMBL164980 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3532448-B1 ADDITIVE FOR CONSTRUCTION CHEMICAL COMPOSITIONS BASF SE (DE) 2021-01-27 EP disclosed