SCHEMBL4744014

SCHEMBL4744014

CC(C)(C)C(C(=O)O)[C@](N)(C(=O)O)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
MAPT P10636 1/20 0.33
PTGS1 P23219 1/20 0.33
SLC7A5 Q01650 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9557686 1.00 ALDH1A1 (0.33) ALDH1A1MAPTPTGS1SLC7A5TSHR
SCHEMBL22921186 0.76 ALDH1A1 (0.36) ALDH1A1MAPTPTGS1SLC7A5TSHR
SCHEMBL6362919 0.76 ALDH1A1 (0.36) ALDH1A1MAPTPTGS1SLC7A5TSHR
SCHEMBL4553889 0.74 ALDH1A1 (0.39) ALDH1A1MAPTPTGS1SLC7A5TSHR
SCHEMBL15917740 0.73 CYP1A2 (0.39) ALDH1A1MAPTPTGS1SLC7A5TSHR
SCHEMBL4018610 0.71 CYP1A2 (0.38) ALDH1A1MAPTPTGS1TSHR
SCHEMBL4021095 0.71 CYP1A2 (0.38) ALDH1A1MAPTPTGS1TSHR
Acetic Acid SCHEMBL9130936 0.71 ALDH1A1 (0.32) ALDH1A1MAPTPTGS1SLC7A5TSHR
SCHEMBL4831119 0.70 ALDH1A1 (0.38) ALDH1A1MAPTPTGS1SLC7A5TSHR
SCHEMBL5176547 0.70 ALDH1A1 (0.39) ALDH1A1MAPTPTGS1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008098056-A2 HIGH RELAXIVITY CHELATES EPIX PHARMACEUTICALS, INC. (US) 2008-08-14 WO disclosed