SCHEMBL2292120

SCHEMBL2292120

C=C[Si](O)(Cc1ccccc1)C1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 3/20 0.38
ALDH1A1 P00352 5/20 0.38
KDM4E B2RXH2 3/20 0.38
G6PC1 P35575 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2B Q13224 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
EPHX1 P07099 1/20 0.36
HPGD P15428 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
ALOX12 P18054 3/20 0.35
KMT2A Q03164 2/20 0.35
HRH3 Q9Y5N1 1/20 0.35
MEN1 O00255 1/20 0.35
GAA P10253 1/20 0.35
HTT P42858 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CYP19A1 P11511 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2289560 0.80 G6PC1 (0.37) EPHX2ALDH1A1KDM4EG6PC1GRIN1
SCHEMBL2289405 0.72 HPGD (0.32) EPHX2ALDH1A1RAB9AEPHX1HPGD
SCHEMBL29275474 0.72 CYP19A1 (0.41) EPHX2ALDH1A1KDM4EG6PC1NPC1
SCHEMBL8680443 0.72 USP2 (0.39) EPHX2ALDH1A1G6PC1RAB9AHPGD
SCHEMBL1315840 0.71 G6PC1 (0.35) EPHX2ALDH1A1G6PC1HPGDHRH3
SCHEMBL1313976 0.71 G6PC1 (0.35) EPHX2ALDH1A1G6PC1KMT2AHRH3
SCHEMBL2287852 0.71 ADH1C (0.31) ALDH1A1
SCHEMBL8761998 0.70 TSHR (0.39) ALDH1A1GAA
SCHEMBL15302819 0.70 TSHR (0.39) ALDH1A1GAA
SCHEMBL2295123 0.70 TSHR (0.39) ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8268489-B2 Non-aqueous electrolyte solution for lithium secondary battery and lithium secondary battery comprising the same LG CHEM, LTD. (KR) 2012-09-18 US claimed
US-20110206999-A1 NON-AQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY COMPRISING THE SAME LG CHEM, LTD. (KR) 2011-08-25 US claimed
US-8268489-B2 Non-aqueous electrolyte solution for lithium secondary battery and lithium secondary battery comprising the same LG CHEM, LTD. (KR) 2012-09-18 US disclosed
US-20110206999-A1 NON-AQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY COMPRISING THE SAME LG CHEM, LTD. (KR) 2011-08-25 US disclosed