SCHEMBL22922079

SCHEMBL22922079

O=C(O)CSCCCCCOCCCCCSCC(=O)O

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GMNN O75496 1/20 0.61
TP53 P04637 1/20 0.61
POLB P06746 1/20 0.61
MAPT P10636 1/20 0.61
THRB P10828 1/20 0.61
CYP2C9 P11712 1/20 0.61
BLM P54132 1/20 0.61
HSD17B10 Q99714 1/20 0.61
CYP2D6 P10635 1/20 0.46
HIF1A Q16665 1/20 0.46
MVD P53602 1/20 0.42
CES2 O00748 3/20 0.41
FAAH O00519 4/20 0.40
CES1 P23141 4/20 0.40
PLA2G6 O60733 1/20 0.40
PLA2G4B P0C869 6/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
BHMT Q93088 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22922154 0.98 GMNN (0.57) GMNNTP53POLBMAPTTHRB
SCHEMBL29313355 0.91 GMNN (0.61) GMNNTP53POLBMAPTTHRB
SCHEMBL23733922 0.88 GMNN (0.49) GMNNTP53POLBMAPTTHRB
SCHEMBL6231607 0.86 HSD17B10 (0.77) GMNNTP53POLBMAPTTHRB
SCHEMBL2807324 0.86 HSD17B10 (0.77) GMNNTP53POLBMAPTTHRB
SCHEMBL5597990 0.86 HSD17B10 (0.77) GMNNTP53POLBMAPTTHRB
SCHEMBL22921976 0.84 HSD17B10 (0.74) GMNNTP53POLBMAPTTHRB
SCHEMBL8666564 0.83 HSD17B10 (0.73) GMNNTP53POLBMAPTTHRB
SCHEMBL22922013 0.81 HSD17B10 (0.70) GMNNTP53POLBMAPTTHRB
Hydrochloric Acid SCHEMBL11144143 0.81 HSD17B10 (0.70) GMNNTP53POLBMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11737995-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease ESPERVITA THERAPEUTICS, INC. (US) 2023-08-29 US disclosed
US-11737995-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease ESPERVITA THERAPEUTICS, INC. (US) 2023-08-29 US disclosed
US-11730712-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease ESPERVITA THERAPEUTICS, INC. (US) 2023-08-22 US disclosed
US-11730712-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease ESPERVITA THERAPEUTICS, INC. (US) 2023-08-22 US disclosed
US-20230007838-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE ESPERVITA THERAPEUTICS, INC. 2023-01-12 US disclosed
US-20220402851-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE ESPERVITA THERAPEUTICS, INC. 2022-12-22 US disclosed
EP-4003314-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS USEFUL FOR THE PREVENTION OR TREATMENT OF DISEASE Espervita Therapeutics, Inc. (US) 2022-06-01 EP disclosed
US-11267778-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and their use for the prevention or treatment of disease ESPERVITA THERAPEUTICS, INC. (US) 2022-03-08 US disclosed
CN-114126593-A Functionalized long chain hydrocarbon mono-and dicarboxylic acids useful for preventing or treating disease 埃斯佩尔维塔治疗股份有限公司 2022-03-01 CN disclosed
US-11084773-B1 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and their use for the prevention or treatment of disease ESPERVITA THERAPEUTICS, INC. (US) 2021-08-10 US disclosed
US-11084773-B1 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and their use for the prevention or treatment of disease ESPERVITA THERAPEUTICS, INC. (US) 2021-08-10 US disclosed
US-20210221765-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE ESPERVITA THERAPEUTICS, INC. 2021-07-22 US disclosed
US-20210024447-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE ESPERVITA THERAPEUTICS, INC. 2021-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230007838-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE CPT1A, PPARG, PC GMNN 1919/4885TP53 522/4885POLB 2084/4885
US-11267778-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and their use for the prevention or treatment of disease CPT1A, PPARG, PC GMNN 1947/4885TP53 523/4885POLB 2088/4885
US-20210221765-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE CPT1A, PPARG, PC GMNN 1947/4885TP53 523/4885POLB 2088/4885
US-11737995-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease AHR, PKD1, CFTR GMNN 2031/4885TP53 2266/4885POLB 2997/4885
US-11084773-B1 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and their use for the prevention or treatment of disease CPT1A, PPARG, PC GMNN 1947/4885TP53 523/4885POLB 2088/4885
US-11730712-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease CPT1A, PPARG, PC GMNN 1975/4885TP53 597/4885POLB 2007/4885
US-20210024447-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE CPT1A, PPARG, PC GMNN 1947/4885TP53 523/4885POLB 2088/4885
US-20220402851-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE CPT1A, PPARG, PC GMNN 1919/4885TP53 522/4885POLB 2084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.