Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | GMNN | O75496 | 1/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | MAPT | P10636 | 1/20 | 0.77 |
| ▸ | THRB | P10828 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | BLM | P54132 | 1/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | BHMT | Q93088 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | CES1 | P23141 | 4/20 | 0.43 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2807324 | 1.00 | HSD17B10 (0.77) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL6231607 | 1.00 | HSD17B10 (0.77) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL22921976 | 0.97 | HSD17B10 (0.74) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL8666564 | 0.97 | HSD17B10 (0.73) | HSD17B10GMNNTP53POLBMAPT | |
| Hydrochloric Acid SCHEMBL11144143 | 0.94 | HSD17B10 (0.70) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL22922013 | 0.94 | HSD17B10 (0.70) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL15282760 | 0.91 | HSD17B10 (0.65) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL8025679 | 0.90 | THRB (0.65) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL10604063 | 0.90 | GMNN (0.65) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL6866607 | 0.90 | THRB (0.65) | HSD17B10GMNNTP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282397-B1 | USE OF COMPOUNDS CONTAINING A THIO-ETHER, SULPHOXIDE OR SULPHONE FUNCTION AS COSMETIC ANTI-POLLUTION AGENT | OREAL (FR) | 2005-05-04 | — | — | EP | claimed |
| US-20040037856-A1 | Use of compounds containing a thio-ether, sulphoxide or sulphone function as cosmetic anti-pollution agent | L'OREAL (FR) | 2004-02-26 | — | — | US | claimed |
| CN-117120093-A | A pharmaceutical composition for preventing and treating dyslipidemia or cardiovascular diseases | 兴和株式会社 | 2023-11-24 | — | — | CN | disclosed |
| EP-1406660-B1 | COMBINATION OF AN ALDOSTERONE RECEPTOR ANTAGONIST AND AN HMG COA REDUCTASE INHIBITOR | PHARMACIA CORP (US) | 2007-06-06 | — | — | EP | disclosed |
| US-20060003975-A1 | Combination of an aldosterone receptor antagonist and an HMG CoA reductase inhibitor | PHARMACIA CORPORATION | 2006-01-05 | — | — | US | disclosed |
| CN-1537019-A | Medical combination of aldosterone receptor antagonist and HMG CoA reductase inhibitor | �ź㴫 | 2004-10-13 | — | — | CN | disclosed |
| CN-1527709-A | Therapeutic combination for cardiovascular and inflammatory indications | — | 2004-09-08 | — | — | CN | disclosed |
| US-20040037856-A1 | Use of compounds containing a thio-ether, sulphoxide or sulphone function as cosmetic anti-pollution agent | L'OREAL (FR) | 2004-02-26 | — | — | US | disclosed |
| US-6264938-B1 | ADMINISTERING POLYDIALLYLAMINE AND HYDROXY-3-METHYLGLUTARYL/3-/, COENZYME A REDUCTASE | GELTEX PHARMACEUTICALS, INC. | 2001-07-24 | — | — | US | disclosed |
| EP-0129527-B1 | VULCANISABLE RUBBER COMPOSITION AND COMPOUNDS USEFUL AS STABILISING AGENTS FOR RUBBER VULCANISATES | MONSANTO EUROPE S.A./N.V. (BE) | 1989-07-12 | — | — | EP | disclosed |
| US-4657956-A | Compounds useful as stabilizing agents for rubber vulcanizates | MONSANTO EUROPE, S. A. (BE) | 1987-04-14 | — | — | US | disclosed |
| US-4595721-A | Vulcanizable rubber composition comprising diene rubber, sulfur, accelerator, and stabilizer | MONSANTO EUROPE, S.A. (BE) | 1986-06-17 | — | — | US | disclosed |
| EP-0129527-A2 | Vulcanisable rubber composition and compounds useful as stabilising agents for rubber vulcanisates | MONSANTO EUROPE S.A./N.V. (BE) | 1984-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040037856-A1 | Use of compounds containing a thio-ether, sulphoxide or sulphone function as cosmetic anti-pollution agent | TST, STS, MPST | HSD17B10 621/4885GMNN 3860/4885TP53 364/4885 |
| US-20060003975-A1 | Combination of an aldosterone receptor antagonist and an HMG CoA reductase inhibitor | HMGCR, NR3C2, LDLR | HSD17B10 53/4885GMNN 4642/4885TP53 4602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.