Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CD44 | P16070 | 1/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 7/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3303530 | 0.86 | ALDH1A1 (0.47) | ALDH1A1GAAMAPTKDM4ELMNA | |
| SCHEMBL1314635 | 0.83 | CYP3A4 (0.55) | ALDH1A1MAPTKDM4ERAPGEF4TSHR | |
| SCHEMBL234943 | 0.80 | CYP3A4 (0.58) | RAPGEF4TSHRCYP3A4ALOX15CHRM1 | |
| SCHEMBL5528095 | 0.79 | CASP1 (0.44) | ALDH1A1GAAMAPTKDM4ETDP1 | |
| SCHEMBL2670000 | 0.79 | CYP3A4 (0.52) | ALDH1A1GAAMAPTTDP1CD44 | |
| SCHEMBL2669824 | 0.79 | CD44 (0.44) | ALDH1A1GAAMAPTKDM4ELMNA | |
| SCHEMBL2972493 | 0.77 | CYP3A4 (0.55) | RAPGEF4TSHRCYP3A4ALOX15CHRM1 | |
| SCHEMBL27561995 | 0.77 | CYP3A4 (0.55) | RAPGEF4TSHRCYP3A4ALOX15CHRM1 | |
| SCHEMBL23205852 | 0.75 | CD44 (0.41) | ALDH1A1GAAMAPTKDM4ETDP1 | |
| SCHEMBL3789961 | 0.75 | CYP3A4 (0.68) | ALDH1A1GAAMAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760762-B2 | Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors | SIGNALRX PHARMACEUTICALS, INC. (US) | 2023-09-19 | — | — | US | disclosed |
| US-20230119573-A1 | GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION APPARATUS, AND POLYIMIDE COMPOUND | FUJIFILM CORPORATION (JP) | 2023-04-20 | — | — | US | disclosed |
| WO-2021014365-A1 | MACROCYCLIC COMPOUNDS AS STING AGONISTS AND METHODS AND USES THEREOF | LUPIN LIMITED (IN) | 2021-01-28 | — | — | WO | disclosed |
| CN-101370777-A | Process for preparing imino compounds | BASELL POLYOLEFINE GMBH (DE) | 2009-02-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760762-B2 | Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors | CDK1, CDKN1A, CDKL1 | ALDH1A1 3077/4885GAA 4060/4885MAPT 1778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.