Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.63 |
| ▸ | GLP1R | P43220 | 8/20 | 0.61 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.57 |
| ▸ | TLR2 | O60603 | 1/20 | 0.57 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.56 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.56 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.55 |
| ▸ | NMT2 | O60551 | 1/20 | 0.51 |
| ▸ | NMT1 | P30419 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15085165 | 0.93 | GLP1R (0.64) | GLP1RLPAR3TLR2NOD1LPAR1 | |
| SCHEMBL14642513 | 0.92 | GLP1R (0.63) | GLP1RLPAR3TLR2NOD1LPAR1 | |
| SCHEMBL18889446 | 0.91 | GLP1R (0.62) | GLP1RLPAR3TLR2NOD1LPAR1 | |
| SCHEMBL18889580 | 0.91 | GLP1R (0.62) | GLP1RLPAR3TLR2NOD1LPAR1 | |
| SCHEMBL15369080 | 0.90 | GLP1R (0.61) | GLP1RLPAR3TLR2NOD1LPAR1 | |
| SCHEMBL20542805 | 0.89 | LPAR3 (0.65) | GLP1RLPAR3TLR2NOD1LPAR1 | |
| SCHEMBL20542804 | 0.89 | LPAR3 (0.65) | GLP1RLPAR3TLR2NOD1LPAR1 | |
| SCHEMBL23443071 | 0.88 | GLP1R (0.60) | GLP1RLPAR3TLR2NOD1LPAR1 | |
| SCHEMBL22386556 | 0.88 | NAAA (0.61) | NAAAGLP1RTLR2NOD1 | |
| SCHEMBL15720863 | 0.88 | SIRT6 (0.64) | GLP1RLPAR3TLR2NOD1LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021013693-A1 | ANTIBODY DRUG CONJUGATES (ADCS) WITH NAMPT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-01-28 | — | — | WO | disclosed |