Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22923941 | 0.91 | MAPT (0.38) | MEN1KMT2AALDH1A1HPGDMTNR1A | |
| SCHEMBL22923870 | 0.82 | MEN1 (0.48) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL22923868 | 0.80 | MEN1 (0.48) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL22923869 | 0.78 | MTNR1A (0.42) | MEN1KMT2AALDH1A1HPGDMTNR1A | |
| SCHEMBL22923882 | 0.78 | MEN1 (0.44) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL22923932 | 0.77 | MEN1 (0.43) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL30367378 | 0.75 | MEN1 (0.55) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL22923865 | 0.73 | MEN1 (0.53) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL22923921 | 0.71 | PTPN1 (0.37) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL22923862 | 0.71 | MEN1 (0.56) | MEN1KMT2AALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012717-A1 | ANTITUMOR COMPOUND USED AS AXL INHIBITOR AND USE THEREOF | 南京华威医药科技集团有限公司 | 2021-01-28 | — | — | WO | disclosed |