Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22923865 | 0.86 | MEN1 (0.53) | MEN1KMT2ALMNAKDM4EL3MBTL1 | |
| SCHEMBL30367422 | 0.85 | LMNA (0.51) | MEN1KMT2ALMNAKDM4EL3MBTL1 | |
| SCHEMBL22923862 | 0.83 | MEN1 (0.56) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL22923843 | 0.82 | MEN1 (0.49) | MEN1KMT2ALMNAKDM4EL3MBTL1 | |
| SCHEMBL22923944 | 0.82 | MEN1 (0.50) | MEN1KMT2ALMNAKDM4EL3MBTL1 | |
| SCHEMBL22923868 | 0.81 | MEN1 (0.48) | MEN1KMT2ALMNAKDM4EL3MBTL1 | |
| SCHEMBL22923870 | 0.81 | MEN1 (0.48) | MEN1KMT2ALMNAKDM4EL3MBTL1 | |
| SCHEMBL29812285 | 0.78 | MEN1 (0.44) | MEN1KMT2ALMNAKDM4EL3MBTL1 | |
| SCHEMBL22923930 | 0.78 | MEN1 (0.45) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL23147394 | 0.77 | LMNA (0.46) | MEN1KMT2ALMNAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023155886-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-08-24 | — | — | WO | disclosed |
| CN-116437918-A | Pyrazolopyridine compounds as TAM inhibitors | 上海德琪医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |