⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3117265 | 1.00 | — | — | |
| SCHEMBL16638803 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL978525 | 0.98 | DGAT1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL978527 | 0.98 | DGAT1 (0.38) | — | |
| SCHEMBL27506473 | 0.81 | DGAT1 (0.37) | — | |
| SCHEMBL6591463 | 0.81 | DGAT1 (0.37) | — | |
| SCHEMBL485077 | 0.80 | — | — | |
| SCHEMBL12116983 | 0.80 | — | — | |
| SCHEMBL485564 | 0.80 | — | — | |
| SCHEMBL2028469 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110072860-B | Compounds useful as immunomodulators | 百时美施贵宝公司 | 2022-09-02 | — | — | CN | claimed |
| EP-1317417-A2 | 2-AMINO-2-ALKYL-3 HEPTENOIC AND HEPTYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | Pharmacia Corporation (US) | 2003-06-11 | — | — | EP | claimed |
| US-20020072630-A1 | 2-amino-2-alkyl-3 heptenoic and heptynoic acid derivatives useful as nitric oxide synthase inhibitors | PHARMACIA CORPORATION | 2002-06-13 | — | — | US | claimed |
| WO-2002022558-A2 | 2-AMINO-2-ALKYL-3 HEPTENOIC AND HEPTYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | PHARMACIA CORPORATION (US) | 2002-03-21 | — | — | WO | claimed |
| US-20250376468-A1 | PYRAZOLO[1,5-a]PYRIDINE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | UNIV LEUVEN KATH (BE) | 2025-12-11 | — | — | US | disclosed |
| WO-2025111414-A1 | TRPM3-MODULATING BENZOFURAN DERIVATIVES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2025-05-30 | — | — | WO | disclosed |
| CN-119998280-A | Pyrazolo [1,5-a ] pyridine derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2025-05-13 | — | — | CN | disclosed |
| EP-4499636-A2 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | Katholieke Universiteit Leuven KU Leuven Research & Development (BE) | 2025-02-05 | — | — | EP | disclosed |
| CN-116234550-B | Aromatic formyl substituted tricyclic compound and preparation method and application thereof | 劲方医药科技(上海)股份有限公司 | 2024-12-27 | — | — | CN | disclosed |
| US-20240360154-A1 | AROYL SUBSTITUTED TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | ZHEJIANG GENFLEET THERAPEUTICS CO., LTD. (CN) | 2024-10-31 | — | — | US | disclosed |
| CN-115466251-B | Condensed heterocyclic compound, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-06-21 | — | — | CN | disclosed |
| CN-114591318-B | Pyrazolo heterocyclic compound, preparation method thereof, pharmaceutical composition and application | 中国医学科学院药物研究所 | 2024-06-21 | — | — | CN | disclosed |
| US-7241790-B2 | Compounds active in spinigosine 1-phosphate signaling | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241790-B2 | Compounds active in spinigosine 1-phosphate signaling | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-20070088002-A1 | Orally available sphingosine 1-phosphate receptor agonists and antagonists | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-04-19 | — | — | US | disclosed |
| US-20070088002-A1 | Orally available sphingosine 1-phosphate receptor agonists and antagonists | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-04-19 | — | — | US | disclosed |
| US-20050222422-A1 | Compounds active in spinigosine 1-phosphate signaling | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2005-10-06 | — | — | US | disclosed |
| EP-1546110-A2 | COMPOUNDS ACTIVE IN SPHINGOSINE 1-PHOSPHATE SIGNALING | University of Virginia Patent Foundation (US) | 2005-06-29 | — | — | EP | disclosed |
| WO-2005041899-A2 | ORALLY AVAILABLE SPHINGOSINE 1-PHOSPHATE RECEPTOR AGONISTS AND ANTAGONISTS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2005-05-12 | — | — | WO | disclosed |
| WO-2004010949-A2 | COMPOUNDS ACTIVE IN SPINIGOSINE 1-PHOSPHATE SIGNALING | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2004-02-05 | — | — | WO | disclosed |