⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2028469 | 1.00 | — | — | |
| SCHEMBL485564 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL4390742 | 0.98 | DGAT1 (0.43) | — | |
| Hydrochloric Acid SCHEMBL485076 | 0.98 | DGAT1 (0.43) | — | |
| Hydrochloric Acid SCHEMBL30832452 | 0.98 | DGAT1 (0.43) | — | |
| Hydrochloric Acid SCHEMBL485563 | 0.98 | DGAT1 (0.43) | — | |
| Hydrochloric Acid SCHEMBL485078 | 0.98 | DGAT1 (0.43) | — | |
| Iodomethane SCHEMBL7525092 | 0.95 | DGAT1 (0.41) | — | |
| SCHEMBL16297377 | 0.82 | ALDH1A1 (0.32) | — | |
| SCHEMBL2304603 | 0.81 | LMNA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048912-B2 | Benzopyran derivatives having inhibitory activities against liver fibrosis and cirrhosis and their pharmaceutical uses | SK CHEMICALS CO., LTD. (KR) | 2011-11-01 | — | — | US | claimed |
| US-20090118302-A1 | Novel Benzopyran Derivatives Having Inhibitory Activities Against Liver Fibrosis and Cirrhosis and Their Pharmaceutical Uses | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-05-07 | — | — | US | claimed |
| WO-2006070984-A1 | NOVEL BENZOPYRAN DERIVATIVES HAVING INHIBITORY ACTIVITIES AGAINST LIVER FIBROSIS AND CIRRHOSIS AND THEIR PHARMACEUTICAL USES | SK CHEMICALS, CO., LTD. (KR) | 2006-07-06 | — | — | WO | claimed |
| EP-3141548-B9 | PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES | VERTEX PHARMA (US) | 2020-08-12 | — | — | EP | disclosed |
| EP-3141548-B1 | PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES | VERTEX PHARMA (US) | 2020-04-08 | — | — | EP | disclosed |
| US-20180021336-A1 | IMIDAZOLIDINEDIONE DERIVATIVES | AUTIFONY THERAPEUTICS LIMITED (GB) | 2018-01-25 | — | — | US | disclosed |
| US-9849131-B2 | Imidazolidinedione derivatives | AUTIFONY THERAPEUTICS LIMITED (GB) | 2017-12-26 | — | — | US | disclosed |
| CN-104185477-B | Cytotoxic peptides and antibody-drug conjugates thereof | 辉瑞公司 | 2017-05-24 | — | — | CN | disclosed |
| EP-3141548-A1 | PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES | Vertex Pharmaceuticals Incorporated (US) | 2017-03-15 | — | — | EP | disclosed |
| US-20170065585-A1 | IMIDAZOLIDINEDIONE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2017-03-09 | — | — | US | disclosed |
| US-20170065585-A1 | IMIDAZOLIDINEDIONE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2017-03-09 | — | — | US | disclosed |
| US-20090118302-A1 | Novel Benzopyran Derivatives Having Inhibitory Activities Against Liver Fibrosis and Cirrhosis and Their Pharmaceutical Uses | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-05-07 | — | — | US | disclosed |
| US-20080090854-A1 | CXCR2 INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-04-17 | — | — | US | disclosed |
| US-20080090854-A1 | CXCR2 INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-04-17 | — | — | US | disclosed |
| US-20080090854-A1 | CXCR2 INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-04-17 | — | — | US | disclosed |
| EP-1836158-A1 | FUSED BICYCLIC CARBOXAMIDE DERIVATIVES FOR USE AS CXCR2 INHIBITORS IN THE TREATMENT OF INFLAMMATION | Sanofi-Aventis Deutschland GmbH (DE) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006070984-A1 | NOVEL BENZOPYRAN DERIVATIVES HAVING INHIBITORY ACTIVITIES AGAINST LIVER FIBROSIS AND CIRRHOSIS AND THEIR PHARMACEUTICAL USES | SK CHEMICALS, CO., LTD. (KR) | 2006-07-06 | — | — | WO | disclosed |
| WO-2006069656-A1 | FUSED BICYCLIC CARBOXAMIDE DERIVATIVES FOR USE AS CXCR2 INHIBITORS IN THE TREATMENT OF INFLAMMATION | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-07-06 | — | — | WO | disclosed |
| CN-1089549-C | N-acetonylbenzamide fungicides | DOW AGRICULTURE CO LTD (US) | 2002-08-28 | — | — | CN | disclosed |
| CN-1173278-A | N-acetonylbenzamide fungicides | ROHM & HAAS (US) | 1998-02-18 | — | — | CN | disclosed |