SCHEMBL2292444

SCHEMBL2292444

c1ccc(-c2nc3ccsc3nc2-c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.46
L3MBTL1 Q9Y468 5/20 0.46
LMNA P02545 4/20 0.46
KMT2A Q03164 3/20 0.46
TDP1 Q9NUW8 3/20 0.46
GAA P10253 3/20 0.46
MEN1 O00255 2/20 0.46
AKT1 P31749 1/20 0.43
AKT2 P31751 1/20 0.43
ALDH1A1 P00352 4/20 0.43
ATM Q13315 1/20 0.43
TLR9 Q9NR96 1/20 0.43
PKM P14618 1/20 0.42
ADORA2A P29274 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
HRH4 Q9H3N8 1/20 0.40
MAPT P10636 1/20 0.40
NPC1 O15118 1/20 0.40
HPGD P15428 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17865293 0.75 NTRK1 (0.37) L3MBTL1KMT2AADORA2AMAPTPDPK1
SCHEMBL14164355 0.74 RPS6KB2 (0.59) KDM4EL3MBTL1LMNAKMT2ATDP1
SCHEMBL13181730 0.74 ADORA2A (0.38) KDM4ELMNAALDH1A1ADORA2AMAPT
SCHEMBL7736839 0.74 KDM4E (0.54) KDM4EL3MBTL1LMNATDP1ALDH1A1
SCHEMBL29847520 0.74 MAPT (0.52) KDM4EL3MBTL1LMNAKMT2ATDP1
SCHEMBL732131 0.73 KDM4E (0.74) KDM4EL3MBTL1LMNAKMT2ATDP1
SCHEMBL29382173 0.73 KDM4E (0.74) KDM4EL3MBTL1LMNAKMT2ATDP1
SCHEMBL27852277 0.72 SMN1; SMN2 (0.49) KDM4EGAAALDH1A1TLR9ADORA2A
SCHEMBL28710728 0.71 KDM4E (0.71) KDM4EL3MBTL1LMNAKMT2ATDP1
SCHEMBL865711 0.71 KDM4E (0.71) KDM4EL3MBTL1LMNAKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2253034-A1 AIR STABLE PHOTOVOLTAIC DEVICE The Technical University of Denmark (DTU) (DK) 2010-11-24 EP claimed
WO-2009103705-A1 AIR STABLE PHOTOVOLTAIC DEVICE THE TECHNICAL UNIVERSITY OF DENMARK (DK) 2009-08-27 WO claimed
CN-112321806-B Conjugated polymer containing thieno [3,4-b ] pyrazine and preparation method and application thereof 天津理工大学 2023-05-02 CN disclosed
US-20110168549-A1 OPTIMISED SUPPLY SOURCE AND STORAGE UNIT FOR CRYOGENIC POWER OR NANOHYDRIDE ASSISTANCE USING PHOTOVOLTAICS FOR ON-DEMAND ENERGY PRODUCTION SYSTEMS ROUSTAEI ALEX HR 2011-07-14 US disclosed
EP-2253034-A1 AIR STABLE PHOTOVOLTAIC DEVICE The Technical University of Denmark (DTU) (DK) 2010-11-24 EP disclosed
WO-2010018325-A2 OPTIMISED SUPPLY SOURCE AND STORAGE UNIT FOR CRYOGENIC POWER OR NANOHYDRIDE ASSISTANCE USING PHOTOVOLTAICS FOR ON-DEMAND ENERGY PRODUCTION SYSTEMS ROUSTAEI ALEX HR (FR) 2010-02-18 WO disclosed
WO-2009103705-A1 AIR STABLE PHOTOVOLTAIC DEVICE THE TECHNICAL UNIVERSITY OF DENMARK (DK) 2009-08-27 WO disclosed