Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.51 |
| ▸ | KRAS | P01116 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | CCR8 | P51685 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2061612 | 0.77 | KDM4E (0.70) | KDM4ENPC1LMNACCR1CCR5 | |
| SCHEMBL7965339 | 0.75 | KDM4E (0.81) | KDM4ENPC1ADORA1ADORA2ALMNA | |
| SCHEMBL323086 | 0.74 | KDM4E (0.68) | KDM4ENPC1ADORA1ADORA2ALMNA | |
| SCHEMBL2292444 | 0.74 | KDM4E (0.46) | KDM4ENPC1ADORA1ADORA2ALMNA | |
| SCHEMBL7963689 | 0.72 | KDM4E (0.75) | KDM4ENPC1ADORA1ADORA2ALMNA | |
| SCHEMBL3681709 | 0.71 | ADORA1 (0.57) | KDM4ENPC1ADORA1ADORA2ALMNA | |
| SCHEMBL4075083 | 0.71 | KDM4E (1.00) | KDM4ENPC1LMNACCR1CCR5 | |
| SCHEMBL17865293 | 0.70 | NTRK1 (0.37) | ADORA1ADORA2AHTTL3MBTL1MAPK1 | |
| SCHEMBL7919159 | 0.69 | KDM4E (0.59) | KDM4ENPC1LMNACCR1CCR5 | |
| SCHEMBL7952022 | 0.69 | KDM4E (0.70) | KDM4ENPC1ADORA1ADORA2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413658-B1 | THIENO(3,4-B)PYRAZINE-BASED POLYMERS; OPERATES AT LOW VOLTAGE, WITH HIGH STABILITY; EXCELLENT ELECTRON TRANSPORT ABILITIES | FUJI PHOTO FILM CO., LTD. (JP) | 2002-07-02 | — | — | US | disclosed |