Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 14/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.50 |
| ▸ | RELA | Q04206 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21533298 | 0.86 | ALDH1A1 (0.55) | ALDH1A1NPSR1MRGPRX4PLA2G4BTP53 | |
| SCHEMBL14093309 | 0.85 | PLA2G4B (0.67) | ALDH1A1NPSR1MRGPRX4PLA2G4BTP53 | |
| SCHEMBL27733439 | 0.85 | MRGPRX4 (0.57) | ALDH1A1NPSR1MRGPRX4PLA2G4BTP53 | |
| SCHEMBL27450239 | 0.84 | MRGPRX4 (0.56) | ALDH1A1NPSR1MRGPRX4PLA2G4BTP53 | |
| SCHEMBL6000790 | 0.84 | MRGPRX4 (0.68) | ALDH1A1NPSR1MRGPRX4TP53NFKB1 | |
| SCHEMBL11427053 | 0.83 | ALDH1A1 (0.57) | ALDH1A1NPSR1MRGPRX4TP53NFKB1 | |
| SCHEMBL3312463 | 0.81 | MRGPRX4 (0.60) | ALDH1A1NPSR1MRGPRX4PLA2G4BTP53 | |
| SCHEMBL19979109 | 0.81 | SLC7A5 (0.52) | ALDH1A1NPSR1MRGPRX4PLA2G4BSMN1; SMN2 | |
| SCHEMBL25960462 | 0.81 | ALDH1A1 (0.54) | ALDH1A1PLA2G4BSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3311911 | 0.81 | ALDH1A1 (0.52) | ALDH1A1NPSR1MRGPRX4PLA2G4BTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210026246-A1 | COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-01-28 | — | — | US | disclosed |
| CN-101243082-A | Hexahydro-pyrrolo-isoquinoline compounds for the treatment of CNS disorders | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-13 | — | — | CN | disclosed |