Sugi Predict

Sugi Predict / Compounds / SCHEMBL229248

SCHEMBL229248

SCHEMBL229248

O=[N+]([O-])c1cc(F)ccc1Br

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.59
▸ ATM Q13315 1/20 0.59
▸ ALDH1A1 P00352 5/20 0.50
▸ CYP2D6 P10635 1/20 0.50
▸ PDE7A Q13946 1/20 0.46
▸ MAPT P10636 4/20 0.44
▸ KDM4E B2RXH2 2/20 0.44
▸ HSPB1 P04792 3/20 0.44
▸ PKM P14618 1/20 0.44
▸ GAA P10253 1/20 0.43
▸ HTT P42858 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ MAPK1 P28482 2/20 0.42
▸ HIF1A Q16665 1/20 0.42
▸ CYP3A4 P08684 1/20 0.41
▸ KCNMA1 Q12791 1/20 0.41
▸ ABL1 P00519 1/20 0.41
▸ BCR P11274 1/20 0.41
▸ CTSB P07858 1/20 0.41
▸ VCAM1 P19320 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31190183 1.00 TDP1 (0.59) TDP1ATMALDH1A1CYP2D6PDE7A
SCHEMBL40024 0.83 TDP1 (0.64) TDP1ATMALDH1A1PDE7AMAPT
SCHEMBL29449184 0.83 TDP1 (0.64) TDP1ATMALDH1A1PDE7AMAPT
SCHEMBL29974945 0.81 ALDH1A1 (0.49) TDP1ATMALDH1A1CYP2D6MAPT
SCHEMBL29745239 0.80 TDP1 (0.72) TDP1ATMALDH1A1PDE7AHSPB1
SCHEMBL216553 0.80 TDP1 (0.72) TDP1ATMALDH1A1PDE7AHSPB1
SCHEMBL25329112 0.79 ALDH1A1 (0.46) TDP1ATMALDH1A1CYP2D6MAPT
SCHEMBL29462665 0.78 ATM (0.63) TDP1ATMALDH1A1PDE7AMAPT
SCHEMBL102780 0.78 ATM (0.69) TDP1ATMALDH1A1PDE7AMAPT
SCHEMBL29462663 0.78 ATM (0.69) TDP1ATMALDH1A1PDE7AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118851912-A Synthesis method of 2-bromo-5-fluoroacetanilide 浙江江北南海药业有限公司 2024-10-29 — — CN claimed
CN-117903173-B Fluoro indeno-thiophene hole transport material, and preparation method and application thereof 淮阴工学院 2024-09-24 — — CN claimed
CN-117903173-A Fluoro indeno-thiophene hole transport material, and preparation method and application thereof 淮阴工学院 2024-04-19 — — CN claimed
CN-117417867-A Enterobacter cloacae (Enterobacter cloacae) ZJUT16 and application thereof 浙江工业大学 2024-01-19 — — CN claimed
CN-117343948-A Recombinant expression plasmid of nitroreductase EcNTR and application thereof 浙江工业大学 2024-01-05 — — CN claimed
CN-116535408-A Preparation method of carbazole organic electroluminescent host material 安徽秀朗新材料科技有限公司 2023-08-04 — — CN claimed
CN-112110824-B Method for preparing 2-bromo-5-fluoroaniline 上海凌凯医药科技有限公司 2023-04-07 — — CN claimed
CN-110627655-B Synthetic method of 2-bromo-5-fluoro-4-nitroaniline and intermediate thereof 苏州旺山旺水生物医药有限公司 2022-09-20 — — CN claimed
CN-113072552-A Beta-carboline GSK3 beta/DYRK 1A dual inhibitor, preparation method thereof and application thereof in resisting Alzheimer disease 中国人民解放军北部战区总医院 2021-07-06 — — CN claimed
CN-108640842-B Synthetic method of 2-bromo-5-fluoronitrobenzene 大连九信精细化工有限公司 2021-06-04 — — CN claimed
CN-112110824-A Method for preparing 2-bromo-5-fluoroaniline 上海凌凯医药科技有限公司 2020-12-22 — — CN claimed
CN-110627655-A Synthetic method and intermediate of 2-bromo-5-fluoro-4-nitroaniline 苏州旺山旺水生物医药有限公司 2019-12-31 — — CN claimed
CN-106083621-B A kind of synthetic method of the chloro- benzophenone of Amiprol pharmaceutical intermediate 2- amino -5- 成都切斯特科技有限公司 2018-12-04 — — CN claimed
CN-108640842-A A kind of synthetic method of the bromo- 5- fluoronitrobenzenes of 2- 大连九信精细化工有限公司 2018-10-12 — — CN claimed
CN-106083621-A A kind of synthetic method of Amiprol pharmaceutical intermediate 2 amino 5 chloro benzophenone 成都切斯特科技有限公司 2016-11-09 — — CN claimed
CN-105924333-A Synthesizing method for diphenhydramine pharmaceutical intermediate diphenyl carbinol 成都卡迪夫科技有限公司 2016-09-07 — — CN claimed
CN-102875389-A Preparation method of 2-bromo-5-fluoroaniline CHANGZHOU WATSON FINE CHEMICALS CO LTD 2013-01-16 — — CN claimed
US-20260116868-A1 CBL-B INHIBITORS AND METHODS OF USE THEREOF ARCUS BIOSCIENCES, INC. (US) 2026-04-30 — — US disclosed
EP-0119892-B1 HYDROXYL AMINE DERIVATIVES, THEIR PREPARATION, THEIR USE AS GROWTH FACTORS FOR VEGETABLES AND COMPOSITIONS THEREOF ROUSSEL-UCLAF (FR) 1986-08-13 — — EP disclosed
EP-0119892-A1 Hydroxyl amine derivatives, their preparation, their use as growth factors for vegetables and compositions thereof ROUSSEL-UCLAF (FR) 1984-09-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260116868-A1 CBL-B INHIBITORS AND METHODS OF USE THEREOF CBLB, CBLC, CBL TDP1 1843/4885ATM 3423/4885ALDH1A1 3286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.