Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.45 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29449184 | 1.00 | TDP1 (0.64) | TDP1ATMMAPTGAAHTT | |
| SCHEMBL31190183 | 0.83 | TDP1 (0.59) | TDP1ATMMAPTGAAHTT | |
| SCHEMBL229248 | 0.83 | TDP1 (0.59) | TDP1ATMMAPTGAAHTT | |
| SCHEMBL29745239 | 0.80 | TDP1 (0.72) | TDP1ATMHSPB1MAPK1PDE7A | |
| SCHEMBL216553 | 0.80 | TDP1 (0.72) | TDP1ATMHSPB1MAPK1PDE7A | |
| SCHEMBL4641179 | 0.78 | SIRT6 (0.60) | MAPTL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL165733 | 0.78 | CYP19A1 (0.49) | TDP1ATMMAPTCYP19A1AAK1 | |
| SCHEMBL29385912 | 0.78 | TDP1 (1.00) | TDP1ATMHSPB1MAPK1PDE7A | |
| SCHEMBL57112 | 0.78 | TDP1 (1.00) | TDP1ATMHSPB1MAPK1PDE7A | |
| SCHEMBL29431838 | 0.78 | CYP19A1 (0.49) | TDP1ATMMAPTCYP19A1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 761 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178264-A | Synthesis method of bixafen | 西安近代化学研究所 | 2023-05-30 | — | — | CN | claimed |
| CN-109369411-A | A kind of preparation method of the bromo- 4- bromo nitrobenzene phenol of 3- | 常州大学 | 2019-02-22 | — | — | CN | claimed |
| CN-108031441-A | There is the modified activated carbon absorbent of absorption property to the orthophosphates in water body | 北京益清源环保科技有限公司 | 2018-05-15 | — | — | CN | claimed |
| CN-104016875-B | A kind of synthetic method of 5-[4-(2,4-dibromo-phenoxy base)-3-bromophenyl] methane amide butyric acid | JIANGNAN UNIVERSITY (CN) | 2015-12-09 | — | — | CN | claimed |
| CN-104016875-A | Synthesis method of 5-[4-(2,4-dibromophenoxy)-3-bromophenyl]formamidobutyric acid | UNIV JIANGNAN | 2014-09-03 | — | — | CN | claimed |
| CN-102199099-B | Method for preparing 3-bromo-4-methoxyaniline | UNIV CHANGZHOU | 2013-12-18 | — | — | CN | claimed |
| CN-117820191-B | Diphenylamine compound and preparation method, application and pharmaceutical composition thereof | FUDAN UNIVERSITY (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-122036699-A | THR-beta modulators and methods of use thereof | 阿利戈斯治疗公司 | 2026-05-15 | — | — | CN | disclosed |
| EP-4741383-A1 | COMPOUND AND USE THEREOF AS ANTI-CANCER DRUG | Tyligand Bioscience (Shanghai) Limited (CN) | 2026-05-13 | — | — | EP | disclosed |
| US-12589156-B2 | Benzimidazole and benzimidazolone based protac compounds for the targeted degradation of leucine rich repeat kinase 2 (LRRK2) | ARVINAS OPERATIONS, INC. (US) | 2026-03-31 | — | — | US | disclosed |
| US-20260085066-A1 | LEUCINE RICH REPEAT KINASE 2 (LRRK2) DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS INC (US) | 2026-03-26 | — | — | US | disclosed |
| US-20260078127-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | BOEHRINGER INGELHEIM INT (DE) | 2026-03-19 | — | — | US | disclosed |
| EP-3983081-B1 | AMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF | DECIPHERA PHARMACEUTICALS LLC (US) | 2026-03-11 | — | — | EP | disclosed |
| EP-1479666-A1 | ESTER COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-20040220191-A1 | Substituted N-aryl heterocycles, process for their preparation and their use as medicaments | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-11-04 | — | — | US | disclosed |
| WO-2004085433-A2 | POSITIVE ALLOSTERIC MODULATORS OF THE NICOTINIC ACETYLCHOLINE RECEPTOR | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-10-07 | — | — | WO | disclosed |
| WO-2004072025-A2 | SUBSTITUTED N-ARYLHETEROCYCLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-08-26 | — | — | WO | disclosed |
| US-20040138273-A1 | Carbocycle based inhibitors of glycogen synthase kinase 3 | CHIRON CORPORATION | 2004-07-15 | — | — | US | disclosed |
| WO-2004037791-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2004-05-06 | — | — | WO | disclosed |
| US-4801717-A | PLANT GROWTH REGULATORS | ROUSSEL UCLAF (FR) | 1989-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220191-A1 | Substituted N-aryl heterocycles, process for their preparation and their use as medicaments | CYP11B2, CYP11B1, CYP1A1 | TDP1 3492/4885ATM 3490/4885MAPT 4824/4885 |
| US-20040138273-A1 | Carbocycle based inhibitors of glycogen synthase kinase 3 | GSK3B, GSK3A, GSKIP | TDP1 630/4885ATM 506/4885MAPT 594/4885 |
| US-20260078127-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | CD38, CD22, CD79B | TDP1 2127/4885ATM 4220/4885MAPT 4832/4885 |
| US-12589156-B2 | Benzimidazole and benzimidazolone based protac compounds for the targeted degradation of leucine rich repeat kinase 2 (LRRK2) | LRRK2, SNCA, PARK7 | TDP1 3310/4885ATM 246/4885MAPT 250/4885 |
| US-20260085066-A1 | LEUCINE RICH REPEAT KINASE 2 (LRRK2) DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | LRRK2, PARK7, NEDD4 | TDP1 1719/4885ATM 535/4885MAPT 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.