Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.70 |
| ▸ | NPC1 | O15118 | 8/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.63 |
| ▸ | MEN1 | O00255 | 10/20 | 0.63 |
| ▸ | POLB | P06746 | 6/20 | 0.63 |
| ▸ | GAA | P10253 | 6/20 | 0.63 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279464 | 0.78 | RAB9A (0.72) | RAB9ANPC1LMNAKDM4EKMT2A | |
| SCHEMBL11279469 | 0.78 | RAB9A (0.72) | RAB9ANPC1LMNAKDM4EKMT2A | |
| SCHEMBL1164784 | 0.73 | MEN1 (0.68) | RAB9ANPC1LMNAKDM4EKMT2A | |
| SCHEMBL6714499 | 0.73 | RAB9A (0.58) | RAB9ANPC1LMNAKDM4EKMT2A | |
| SCHEMBL6714502 | 0.73 | RAB9A (0.58) | RAB9ANPC1LMNAKDM4EKMT2A | |
| SCHEMBL1164785 | 0.73 | MEN1 (0.68) | RAB9ANPC1LMNAKDM4EKMT2A | |
| SCHEMBL2491877 | 0.71 | KMT2A (0.68) | RAB9ANPC1LMNAKDM4EKMT2A | |
| SCHEMBL2491876 | 0.71 | KMT2A (0.68) | RAB9ANPC1LMNAKDM4EKMT2A | |
| SCHEMBL11833203 | 0.71 | RAB9A (0.55) | RAB9ANPC1LMNAKDM4EKMT2A | |
| SCHEMBL11833207 | 0.71 | RAB9A (0.55) | RAB9ANPC1LMNAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012264-A1 | TRIAZOLE SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 东莞市东阳光农药研发有限公司 | 2021-01-28 | — | — | WO | disclosed |