Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.72 |
| ▸ | NPC1 | O15118 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 10/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279469 | 1.00 | RAB9A (0.72) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL11262157 | 0.80 | RAB9A (0.72) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL11262154 | 0.80 | RAB9A (0.72) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL6714499 | 0.78 | RAB9A (0.58) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL22925046 | 0.78 | RAB9A (0.70) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL6714502 | 0.78 | RAB9A (0.58) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL11261524 | 0.78 | MEN1 (0.67) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL11261515 | 0.78 | MEN1 (0.67) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL11267029 | 0.78 | RAB9A (0.68) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL11267026 | 0.78 | RAB9A (0.68) | RAB9ANPC1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329457-A | Process for the preparation of 6-(substituted amino)-3-pyridazinylhydrazines and their salts | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1982-05-11 | — | — | US | disclosed |