Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3174822 | 0.73 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AALDH1A1NPSR1 | |
| SCHEMBL26066559 | 0.73 | — | — | |
| SCHEMBL8946056 | 0.73 | — | — | |
| SCHEMBL8946058 | 0.73 | — | — | |
| SCHEMBL1256043 | 0.72 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL1492176 | 0.72 | RAB9A (0.53) | SMN1; SMN2NPC1RAB9AALDH1A1NPSR1 | |
| SCHEMBL1492175 | 0.72 | RAB9A (0.53) | SMN1; SMN2NPC1RAB9AALDH1A1NPSR1 | |
| SCHEMBL28902600 | 0.72 | RAB9A (0.51) | SMN1; SMN2NPC1RAB9AALDH1A1NPSR1 | |
| SCHEMBL4681800 | 0.71 | NPC1 (0.50) | SMN1; SMN2NPC1RAB9AALDH1A1NPSR1 | |
| SCHEMBL16096921 | 0.71 | PKM (0.49) | SMN1; SMN2NPC1RAB9AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012264-A1 | TRIAZOLE SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 东莞市东阳光农药研发有限公司 | 2021-01-28 | — | — | WO | disclosed |