Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17434732 | 0.77 | MAPT (0.44) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL533849 | 0.77 | MAPT (0.44) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL533848 | 0.77 | MAPT (0.44) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL6448339 | 0.76 | MAPT (0.39) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL6448341 | 0.76 | MAPT (0.39) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL28407169 | 0.76 | MAPT (0.43) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL23863718 | 0.75 | MAPT (0.32) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL5422596 | 0.74 | MAOA (0.37) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL17981123 | 0.73 | KMT2A (0.35) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL17981121 | 0.73 | KMT2A (0.35) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012264-A1 | TRIAZOLE SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 东莞市东阳光农药研发有限公司 | 2021-01-28 | — | — | WO | disclosed |