Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12857796 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTGAAMAOA | |
| SCHEMBL353879 | 0.79 | HTT (0.47) | ALDH1A1KDM4EMAPTGAAMAOA | |
| SCHEMBL353880 | 0.79 | HTT (0.47) | ALDH1A1KDM4EMAPTGAAMAOA | |
| SCHEMBL13644354 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTGAAMAOA | |
| SCHEMBL12651584 | 0.71 | MAPT (0.49) | ALDH1A1KDM4EMAPTGAAMAOA | |
| SCHEMBL9687030 | 0.70 | MEN1 (0.46) | ALDH1A1KDM4EMAPTGAAMAOA | |
| SCHEMBL2594537 | 0.70 | MAPT (0.68) | ALDH1A1KDM4EMAPTGAAMAOA | |
| SCHEMBL29924708 | 0.70 | MAPT (0.68) | ALDH1A1KDM4EMAPTGAAMAOA | |
| SCHEMBL14481557 | 0.70 | MAPT (0.68) | ALDH1A1KDM4EMAPTGAAMAOA | |
| SCHEMBL18439879 | 0.69 | MAPT (0.50) | ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012264-A1 | TRIAZOLE SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 东莞市东阳光农药研发有限公司 | 2021-01-28 | — | — | WO | disclosed |