Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353879 | 0.86 | HTT (0.47) | MEN1KMT2ACYP3A4MAPTEGFR | |
| SCHEMBL353880 | 0.86 | HTT (0.47) | MEN1KMT2ACYP3A4MAPTEGFR | |
| SCHEMBL1027979 | 0.85 | ALDH1A1 (0.49) | MEN1KMT2AABCB1CA1CA2 | |
| SCHEMBL3969245 | 0.85 | ALDH1A1 (0.49) | MEN1KMT2AABCB1CA1CA2 | |
| SCHEMBL1027980 | 0.85 | ALDH1A1 (0.49) | MEN1KMT2AABCB1CA1CA2 | |
| SCHEMBL10458884 | 0.79 | MAPT (0.53) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL18746297 | 0.79 | MAPT (0.53) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL7272150 | 0.78 | MAOB (0.52) | MEN1KMT2ACA1CA2CA7 | |
| SCHEMBL7272155 | 0.78 | MAOB (0.52) | MEN1KMT2ACA1CA2CA7 | |
| SCHEMBL5472320 | 0.77 | KDM4E (0.50) | MEN1KMT2ACYP3A4MAPTEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0179855-B1 | DOPAMINE AGONISTS | Whitby Research Incorporated (US) | 1992-07-29 | — | — | EP | disclosed |
| EP-0179855-A4 | DOPAMINE AGONISTS. | NELSON RES & DEV COMPANY (US) | 1986-08-21 | — | — | EP | disclosed |
| EP-0179855-A1 | DOPAMINE AGONISTS. | NELSON RES & DEV (US) | 1986-05-07 | — | — | EP | disclosed |
| WO-1985004582-A1 | NOVEL DOPAMINE AGONISTS | NELSON RESEARCH AND DEVELOPMENT COMPANY (US) | 1985-10-24 | — | — | WO | disclosed |
| US-4540691-A | Dopamine agonists and use thereof | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1985-09-10 | — | — | US | disclosed |