Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29574775 | 1.00 | HPGD (0.43) | HPGDALDH1A1NPSR1SMN1; SMN2LMNA | |
| SCHEMBL16341669 | 0.92 | LMNA (0.54) | HPGDALDH1A1NPSR1SMN1; SMN2LMNA | |
| SCHEMBL17838414 | 0.92 | CTSD (0.41) | HPGDALDH1A1NPSR1SMN1; SMN2LMNA | |
| SCHEMBL29574409 | 0.92 | CTSD (0.41) | HPGDALDH1A1NPSR1SMN1; SMN2LMNA | |
| SCHEMBL18179373 | 0.90 | HPGD (0.42) | HPGDALDH1A1NPSR1SMN1; SMN2LMNA | |
| SCHEMBL1940843 | 0.89 | HPGD (0.49) | HPGDALDH1A1NPSR1SMN1; SMN2LMNA | |
| SCHEMBL12930769 | 0.88 | ESR1 (0.52) | HPGDALDH1A1NPSR1SMN1; SMN2LMNA | |
| SCHEMBL18170299 | 0.87 | NPC1 (0.44) | HPGDALDH1A1NPSR1SMN1; SMN2LMNA | |
| SCHEMBL16323046 | 0.83 | LMNA (0.44) | HPGDALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL15096954 | 0.83 | HPGD (0.46) | HPGDALDH1A1NPSR1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014915-B2 | Selective estrogen receptor degrader | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2021-05-25 | — | — | US | disclosed |
| US-20210024504-A1 | SELECTIVE ESTROGEN RECEPTOR DEGRADER | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2021-01-28 | — | — | US | disclosed |
| WO-2021014386-A1 | SELECTIVE ESTROGEN RECEPTOR DEGRADER | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2021-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210024504-A1 | SELECTIVE ESTROGEN RECEPTOR DEGRADER | ESR1, GPER1, ESR2 | HPGD 1358/4885ALDH1A1 1106/4885NPSR1 1232/4885 |
| US-11014915-B2 | Selective estrogen receptor degrader | ESR1, GPER1, ESR2 | HPGD 1358/4885ALDH1A1 1106/4885NPSR1 1232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.