Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.34 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.34 |
| ▸ | ANPEP | P15144 | 5/20 | 0.33 |
| ▸ | LAP3 | P28838 | 3/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26417082 | 0.82 | ALDH1A1 (0.41) | ALDH1A1SLC7A5TDP1RNPEPCACNA2D1 | |
| SCHEMBL9784727 | 0.81 | — | — | |
| SCHEMBL15296659 | 0.81 | — | — | |
| SCHEMBL19821897 | 0.81 | — | — | |
| SCHEMBL15296654 | 0.81 | — | — | |
| SCHEMBL23059624 | 0.79 | RNPEP (0.38) | ALDH1A1SLC7A5RNPEPCACNA2D1CACNB3 | |
| SCHEMBL1561818 | 0.74 | — | — | |
| SCHEMBL4923058 | 0.70 | ALDH1A1 (0.41) | ALDH1A1SLC7A5RNPEPANPEPLAP3 | |
| SCHEMBL878423 | 0.70 | — | — | |
| SCHEMBL27635490 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11447452-B2 | Agonists of peroxisome proliferator-activated receptor alpha and methods of use | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2022-09-20 | — | — | US | disclosed |
| US-11337968-B2 | Phenylquinoline compositions for treatment of ocular disorders and conditions | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2022-05-24 | — | — | US | disclosed |
| US-20210024469-A1 | AGONISTS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA AND METHODS OF USE | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2021-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210024469-A1 | AGONISTS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA AND METHODS OF USE | PPARG, PPARA, PPARD | ALDH1A1 845/4885SLC7A5 3653/4885TDP1 3044/4885 |
| US-11337968-B2 | Phenylquinoline compositions for treatment of ocular disorders and conditions | PPARG, PPARA, PPARD | ALDH1A1 1092/4885SLC7A5 3657/4885TDP1 2244/4885 |
| US-11447452-B2 | Agonists of peroxisome proliferator-activated receptor alpha and methods of use | PPARG, PPARA, PPARD | ALDH1A1 845/4885SLC7A5 3653/4885TDP1 3044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.