⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561818 | 0.78 | — | — | |
| SCHEMBL28142432 | 0.70 | — | — | |
| SCHEMBL15296659 | 0.70 | — | — | |
| SCHEMBL9784727 | 0.70 | — | — | |
| SCHEMBL15296654 | 0.70 | — | — | |
| SCHEMBL24743662 | 0.70 | — | — | |
| SCHEMBL19821897 | 0.70 | — | — | |
| Chloroform SCHEMBL10358242 | 0.67 | — | — | |
| SCHEMBL1036103 | 0.67 | — | — | |
| SCHEMBL6566833 | 0.67 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100537549-C | Process for preparing N-aryl morpholinones | MERCK PATENT GMBH (DE) | 2009-09-09 | — | — | CN | disclosed |
| CN-1832933-A | Method for production of n-aryl morpholinones | MERCK PATENT GMBH (DE) | 2006-09-13 | — | — | CN | disclosed |