SCHEMBL22925129

SCHEMBL22925129

Cc1ncc2c(C)c(C(C)(C)C)cc(C3CCC(C)(C)CC3)c2n1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 1/20 0.33
PDK2 Q15119 1/20 0.33
PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22925130 0.90 PDE10A (0.38) PDK1PDK2PDE10A
SCHEMBL22925133 0.87 PDK1 (0.35) PDK1PDK2PDE10A
SCHEMBL22925190 0.86 PSMB5 (0.35) PDK1PDK2PDE10A
SCHEMBL22925159 0.81 PDK2 (0.32) PDK2
SCHEMBL25814298 0.78 PDE10A (0.30) PDE10A
SCHEMBL22925128 0.75 PDE10A (0.33) PDK1PDK2PDE10A
SCHEMBL22925173 0.74 BRD4 (0.35)
SCHEMBL22925124 0.74 PDK2 (0.32) PDK2
SCHEMBL22925186 0.72 ADRA2A (0.31) PDK2
SCHEMBL22925160 0.72 IDH1 (0.32) PDK2PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230257407-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-08-17 US disclosed
US-20230257407-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-08-17 US disclosed
US-11685754-B2 Heteroleptic organic electroluminescent materials UNIVERSAL DISPLAY CORPORATION (US) 2023-06-27 US disclosed
US-20210024556-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11685754-B2 Heteroleptic organic electroluminescent materials IK, ORC3, CACNA2D2 PDK1 279/4885PDK2 782/4885PDE10A 3899/4885
US-20230257407-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES IK, ORC3, REL PDK1 192/4885PDK2 593/4885PDE10A 3447/4885
US-20210024556-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES IK, ORC3, REL PDK1 192/4885PDK2 593/4885PDE10A 3447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.