Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.39 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19493649 | 1.00 | GAA (0.44) | GAAKDM4EALDH1A1LMNANPC1 | |
| SCHEMBL7669128 | 0.79 | NPC1 (0.40) | ALDH1A1NPC1RAB9AHTTNFE2L2 | |
| SCHEMBL7669124 | 0.79 | NPC1 (0.40) | ALDH1A1NPC1RAB9AHTTNFE2L2 | |
| SCHEMBL19449851 | 0.77 | LMNA (0.39) | GAAKDM4ELMNANPC1RAB9A | |
| SCHEMBL22925027 | 0.77 | LMNA (0.68) | ALDH1A1LMNANPC1RAB9AHTT | |
| SCHEMBL1250674 | 0.76 | DGAT1 (0.39) | ALDH1A1NPC1RAB9AHTTNFE2L2 | |
| SCHEMBL1250677 | 0.76 | DGAT1 (0.39) | ALDH1A1NPC1RAB9AHTTNFE2L2 | |
| SCHEMBL16609588 | 0.75 | KDM4E (0.68) | GAAKDM4EALDH1A1LMNANPC1 | |
| SCHEMBL9355268 | 0.75 | NPC1 (0.40) | GAAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL9355273 | 0.75 | NPC1 (0.40) | GAAKDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012264-A1 | TRIAZOLE SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 东莞市东阳光农药研发有限公司 | 2021-01-28 | — | — | WO | disclosed |