Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.42 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 3/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29620899 | 1.00 | MAOB (0.44) | MAOBMAOACSF1RNPC1RAB9A | |
| SCHEMBL16740400 | 0.86 | CSF1R (0.47) | MAOBCSF1RNPC1RAB9AKIT | |
| SCHEMBL20447822 | 0.84 | NPC1 (0.47) | CSF1RNPC1RAB9AKITAPP | |
| SCHEMBL20607927 | 0.83 | GCK (0.46) | MAOBSMN1; SMN2 | |
| SCHEMBL28988132 | 0.80 | NPC1 (0.49) | MAOBCSF1RNPC1RAB9ANTRK1 | |
| SCHEMBL30388779 | 0.80 | NPC1 (0.49) | MAOBCSF1RNPC1RAB9ANTRK1 | |
| SCHEMBL25385270 | 0.78 | CCR5 (0.46) | MAOBCSF1RNPC1RAB9ANTRK1 | |
| SCHEMBL27177208 | 0.78 | MAOB (0.59) | MAOBMAOACCR5LRRK2APP | |
| SCHEMBL30574868 | 0.78 | CCR5 (0.46) | MAOBCSF1RNPC1RAB9ANTRK1 | |
| SCHEMBL1629163 | 0.78 | USP8 (0.38) | RAB9ADYRK1BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |
| WO-2021012018-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2021-01-28 | — | — | WO | disclosed |