Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.44 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 5/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28988132 | 1.00 | NPC1 (0.49) | NPC1RAB9ALRRK2MAOBABCB1 | |
| SCHEMBL2492632 | 0.82 | GCK (0.49) | RAB9ALRRK2MAOBABCB1CCR5 | |
| SCHEMBL30523230 | 0.82 | GCK (0.49) | RAB9ALRRK2MAOBABCB1CCR5 | |
| SCHEMBL25385270 | 0.82 | CCR5 (0.46) | NPC1RAB9ALRRK2MAOBABCB1 | |
| SCHEMBL30574868 | 0.82 | CCR5 (0.46) | NPC1RAB9ALRRK2MAOBABCB1 | |
| SCHEMBL21327606 | 0.81 | CSF1R (0.50) | NPC1RAB9ALRRK2MAOBNTRK1 | |
| SCHEMBL22925751 | 0.80 | MAOB (0.44) | NPC1RAB9ALRRK2MAOBNTRK1 | |
| SCHEMBL29620899 | 0.80 | MAOB (0.44) | NPC1RAB9ALRRK2MAOBNTRK1 | |
| SCHEMBL25383687 | 0.80 | NPC1 (0.48) | NPC1RAB9ALRRK2MAOBNTRK1 | |
| SCHEMBL190649 | 0.79 | MAOB (0.51) | NPC1RAB9ALRRK2MAOBCCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115989224-B | Plasma kallikrein inhibitors | 默沙东有限责任公司 | 2025-02-25 | — | — | CN | disclosed |
| EP-4499630-A1 | BCL-XL INHIBITORS | BeiGene, Ltd. (KY) | 2025-02-05 | — | — | EP | disclosed |
| CN-118974033-A | Bcl-xL inhibitors | 百济神州有限公司 | 2024-11-15 | — | — | CN | disclosed |
| WO-2023185986-A1 | BCL-XL INHIBITORS | BEIGENE , LTD. (KY) | 2023-10-05 | — | — | WO | disclosed |
| CN-115989224-A | Plasma kallikrein inhibitors | 默沙东有限责任公司 | 2023-04-18 | — | — | CN | disclosed |