Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29620855 | 1.00 | NPSR1 (0.47) | NPSR1KDM4ECASP3KIF11KMT2A | |
| SCHEMBL29620975 | 0.80 | NPSR1 (0.47) | NPSR1KDM4ECASP3KIF11KMT2A | |
| SCHEMBL29620948 | 0.80 | NPSR1 (0.47) | NPSR1KDM4ECASP3KIF11KMT2A | |
| SCHEMBL24636938 | 0.80 | NPSR1 (0.47) | NPSR1KDM4ECASP3KIF11KMT2A | |
| SCHEMBL22925721 | 0.80 | NPSR1 (0.47) | NPSR1KDM4ECASP3KIF11KMT2A | |
| SCHEMBL22925776 | 0.79 | TRPV1 (0.46) | KDM4ECASP3KIF11TRPV1MAPT | |
| SCHEMBL29620857 | 0.77 | CYP1A1 (0.36) | KDM4ETRPV3MAPTNPC1RAB9A | |
| SCHEMBL22925741 | 0.77 | CYP1A1 (0.36) | KDM4ETRPV3MAPTNPC1RAB9A | |
| SCHEMBL29621129 | 0.75 | TRPV4 (0.34) | NPSR1KDM4E | |
| SCHEMBL28733757 | 0.75 | TRPV4 (0.34) | NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |
| WO-2021012018-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2021-01-28 | — | — | WO | disclosed |