Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925721 | 1.00 | NPSR1 (0.47) | NPSR1KDM4EKIF11PDE2AKMT2A | |
| SCHEMBL22925568 | 0.81 | KIF11 (0.48) | KIF11PDE2AKMT2AIKBKB | |
| SCHEMBL29620855 | 0.80 | NPSR1 (0.47) | NPSR1KDM4EKIF11PDE2AKMT2A | |
| SCHEMBL22925930 | 0.80 | NPSR1 (0.47) | NPSR1KDM4EKIF11PDE2AKMT2A | |
| SCHEMBL29620948 | 0.80 | NPSR1 (0.47) | NPSR1KDM4EKIF11PDE2AKMT2A | |
| SCHEMBL24636938 | 0.80 | NPSR1 (0.47) | NPSR1KDM4EKIF11PDE2AKMT2A | |
| SCHEMBL22925606 | 0.77 | CYP1A1 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL29620904 | 0.75 | NPSR1 (0.44) | NPSR1KDM4EKIF11PDE2AKMT2A | |
| SCHEMBL29595709 | 0.75 | NPSR1 (0.53) | NPSR1KDM4EKIF11KMT2AKDM1A | |
| SCHEMBL811160 | 0.75 | NPSR1 (0.53) | NPSR1KDM4EKIF11KMT2AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |