Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 3/20 | 0.36 |
| ▸ | FLT4 | P35916 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | VCP | P55072 | 6/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925613 | 0.84 | TRPV1 (0.36) | ALOX5FLT1FLT4KDRVCP | |
| SCHEMBL29696298 | 0.84 | TRPV1 (0.36) | ALOX5FLT1FLT4KDRVCP | |
| SCHEMBL22925497 | 0.74 | TRPV1 (0.48) | ALOX5FLT1FLT4KDRVCP | |
| SCHEMBL29696323 | 0.74 | TRPV1 (0.48) | ALOX5FLT1FLT4KDRVCP | |
| SCHEMBL22925785 | 0.72 | KDR (0.40) | ALOX5FLT1FLT4KDRVCP | |
| SCHEMBL22925599 | 0.72 | ALOX5 (0.34) | ALOX5KDR | |
| SCHEMBL22925783 | 0.71 | ALOX5 (0.37) | ALOX5FLT1FLT4KDRVCP | |
| SCHEMBL22925594 | 0.71 | ALOX5 (0.37) | ALOX5FLT1FLT4KDRVCP | |
| SCHEMBL28733820 | 0.70 | VCP (0.37) | KDRVCPPIK3CG | |
| SCHEMBL29620935 | 0.70 | P4HTM (0.47) | FLT1FLT4KDRVCPPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012018-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2021-01-28 | — | — | WO | disclosed |