Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 5/20 | 0.44 |
| ▸ | FLT4 | P35916 | 5/20 | 0.44 |
| ▸ | KDR | P35968 | 5/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29620874 | 1.00 | IMPDH2 (0.45) | IMPDH2GSK3BFLT1FLT4KDR | |
| SCHEMBL29620887 | 0.90 | IMPDH2 (0.38) | IMPDH2GSK3BFLT1FLT4KDR | |
| SCHEMBL22925755 | 0.90 | IMPDH2 (0.38) | IMPDH2GSK3BFLT1FLT4KDR | |
| SCHEMBL22925794 | 0.89 | IMPDH2 (0.41) | IMPDH2FLT1FLT4KDRVCP | |
| SCHEMBL29696282 | 0.89 | IMPDH2 (0.41) | IMPDH2FLT1FLT4KDRVCP | |
| SCHEMBL22926054 | 0.87 | GSK3B (0.41) | IMPDH2GSK3BFLT1FLT4KDR | |
| SCHEMBL29621081 | 0.87 | GSK3B (0.41) | IMPDH2GSK3BFLT1FLT4KDR | |
| SCHEMBL22925907 | 0.86 | GSK3B (0.42) | IMPDH2GSK3BPDE2ATRPV1MAPT | |
| SCHEMBL22925873 | 0.83 | IMPDH2 (0.45) | IMPDH2GSK3BFLT1FLT4KDR | |
| SCHEMBL22926080 | 0.83 | IMPDH2 (0.43) | IMPDH2GSK3BFLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |
| WO-2021012018-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2021-01-28 | — | — | WO | disclosed |