Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.45 |
| ▸ | FLT1 | P17948 | 3/20 | 0.41 |
| ▸ | FLT4 | P35916 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925705 | 0.89 | FLT1 (0.46) | IMPDH2FLT1FLT4KDRGSK3B | |
| SCHEMBL22926054 | 0.86 | GSK3B (0.41) | IMPDH2FLT1FLT4KDRGSK3B | |
| SCHEMBL29621081 | 0.86 | GSK3B (0.41) | IMPDH2FLT1FLT4KDRGSK3B | |
| SCHEMBL22926079 | 0.83 | IMPDH2 (0.45) | IMPDH2FLT1FLT4KDRGSK3B | |
| SCHEMBL29620874 | 0.83 | IMPDH2 (0.45) | IMPDH2FLT1FLT4KDRGSK3B | |
| SCHEMBL31755987 | 0.83 | TRPV1 (0.39) | IMPDH2FLT1FLT4KDRGSK3B | |
| SCHEMBL29696276 | 0.83 | TRPV1 (0.42) | IMPDH2FLT1FLT4KDRGSK3B | |
| SCHEMBL28733676 | 0.77 | TRPV1 (0.41) | IMPDH2FLT1FLT4KDRGSK3B | |
| SCHEMBL22926050 | 0.77 | NPSR1 (0.39) | IMPDH2FLT1FLT4KDRGSK3B | |
| SCHEMBL29620970 | 0.77 | NPSR1 (0.39) | IMPDH2FLT1FLT4KDRGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |
| WO-2021012018-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2021-01-28 | — | — | WO | disclosed |