Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8126718 | 0.78 | ESR2 (0.31) | — | |
| SCHEMBL8381883 | 0.78 | — | — | |
| SCHEMBL11495334 | 0.78 | — | — | |
| SCHEMBL23005645 | 0.77 | EPHX1 (0.33) | EPHX1 | |
| SCHEMBL22926475 | 0.76 | LMNA (0.32) | — | |
| SCHEMBL1447877 | 0.75 | — | — | |
| SCHEMBL922299 | 0.74 | ESR2 (0.35) | — | |
| SCHEMBL17621500 | 0.74 | — | — | |
| SCHEMBL23514940 | 0.72 | OPRM1 (0.32) | — | |
| Ethane SCHEMBL1011436 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023193114-A1 | METHODS OF USING ATR INHIBITORS | REPARE THERAPEUTICS INC. (CA) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023109883-A1 | AROMATIC HETEROCYCLE-SUBSTITUTED COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊石医药科技有限公司 | 2023-06-22 | — | — | WO | disclosed |
| WO-2021012049-A1 | SUBSTITUTED 2-MORPHOLINOPYRIDINE DERIVATIVES AS ATR KINASE INHIBITORS | REPARE THERAPEUTICS INC. (CA) | 2021-01-28 | — | — | WO | disclosed |