Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17481627 | 0.88 | NPC1 (0.50) | TSHRHPGDHTR2CBACE1MEN1 | |
| SCHEMBL1929718 | 0.82 | HTR2C (0.48) | TSHRHPGDHTR2CFKBP1ANPC1 | |
| SCHEMBL25804037 | 0.79 | KDM4E (0.36) | HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL20701414 | 0.79 | NPC1 (0.51) | HTR2CMEN1KMT2ANPC1GAA | |
| SCHEMBL14567386 | 0.79 | TSHR (0.52) | TSHRHPGDHTR2CBACE1MEN1 | |
| SCHEMBL1710024 | 0.79 | TSHR (0.52) | TSHRHPGDHTR2CBACE1MEN1 | |
| SCHEMBL20701800 | 0.78 | FAAH (0.48) | TSHRHTR2CNPC1GAAMAPK1 | |
| SCHEMBL20701799 | 0.78 | FAAH (0.48) | TSHRHTR2CNPC1GAAMAPK1 | |
| SCHEMBL17153132 | 0.78 | JAK2 (0.47) | TSHRCTSLPARP1MEN1KMT2A | |
| SCHEMBL15122636 | 0.77 | HPGD (0.45) | CTSLHPGDHTR2CPARP1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210024575-A1 | THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE | SERVIER PHARMACEUTICALS LLC | 2021-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210024575-A1 | THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE | IDH1, IDH3B, IDH3A | TSHR 4517/4885CTSL 2080/4885HPGD 604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.