Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | GFER | P55789 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2294061 | 0.87 | MAPT (0.49) | MAPTKMT2AMEN1GFERGAA | |
| SCHEMBL29452975 | 0.73 | MAPT (0.55) | MAPTKMT2AMEN1GFERRECQL | |
| SCHEMBL123429 | 0.73 | MAPT (0.55) | MAPTKMT2AMEN1GFERRECQL | |
| SCHEMBL6582107 | 0.71 | MAPT (1.00) | MAPTKMT2AMEN1GFERRECQL | |
| SCHEMBL2605855 | 0.70 | MAPT (0.66) | MAPTKMT2AMEN1GFERRECQL | |
| SCHEMBL20986073 | 0.70 | MAPT (0.51) | MAPTKMT2AMEN1GFERRECQL | |
| SCHEMBL7355209 | 0.70 | MAPT (0.54) | MAPTKMT2AMEN1GFERRECQL | |
| SCHEMBL5244966 | 0.69 | MAPT (0.53) | MAPTKMT2AMEN1GFERRECQL | |
| SCHEMBL5244954 | 0.69 | MAPT (0.53) | MAPTKMT2AMEN1GFERRECQL | |
| SCHEMBL6354542 | 0.69 | MAPT (0.56) | MAPTKMT2AMEN1GFERRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003806-B2 | Integrin antagonists useful as anticancer agents | OSI Pharmaceuticals, LLC (US) | 2011-08-23 | — | — | US | disclosed |