Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | GFER | P55789 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29452975 | 1.00 | MAPT (0.55) | MAPTTDP1KMT2AMEN1GFER | |
| SCHEMBL6001204 | 0.93 | GAA (0.53) | MAPTTDP1KMT2AMEN1GFER | |
| SCHEMBL8603744 | 0.83 | PKM (0.50) | MAPTTDP1KMT2AMEN1GFER | |
| SCHEMBL972833 | 0.80 | TDP1 (0.50) | MAPTTDP1KMT2AMEN1GFER | |
| SCHEMBL29390080 | 0.78 | KMT2A (0.65) | MAPTTDP1KMT2AMEN1GFER | |
| SCHEMBL108393 | 0.78 | KMT2A (0.65) | MAPTTDP1KMT2AMEN1GFER | |
| SCHEMBL6232719 | 0.76 | ALDH1A1 (0.65) | MAPTTDP1KMT2AMEN1GFER | |
| SCHEMBL17252293 | 0.75 | MAPT (0.61) | MAPTTDP1KMT2AMEN1GFER | |
| SCHEMBL3858400 | 0.75 | MEN1 (0.52) | MAPTKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL211286 | 0.75 | MAPT (0.61) | MAPTTDP1KMT2AMEN1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 815 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110020251-A1 | Ultraviolet-Absorbing Compounds | AVOCA LLC | 2011-01-27 | — | — | US | claimed |
| US-7799092-B2 | Composition for simultaneously bleaching and dyeing keratin fibers, comprising at least one anionic or nonionic direct dye and at least one associative polymer | L'OREAL S.A. (FR) | 2010-09-21 | — | — | US | claimed |
| US-7736395-B2 | direct dyes | L'OREAL S.A. (FR) | 2010-06-15 | — | — | US | claimed |
| EP-1738800-B1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer | OREAL (FR) | 2010-06-09 | — | — | EP | claimed |
| EP-1738801-B1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid | OREAL (FR) | 2010-06-09 | — | — | EP | claimed |
| EP-2158942-A2 | Direct hair dye composition comprising insoluble oxygenated compounds and processes | L'Oreal (FR) | 2010-03-03 | — | — | EP | claimed |
| US-7651534-B2 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | L'OREAL SA (FR) | 2010-01-26 | — | — | US | claimed |
| EP-1757326-B1 | Direct dying composition comprising insoluble oxygenated compounds and processes | OREAL (FR) | 2009-01-07 | — | — | EP | claimed |
| US-20070044251-A1 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | L'OREAL S.A. (FR) | 2007-03-01 | — | — | US | claimed |
| EP-1757326-A1 | Direct dying composition comprising insoluble oxygenated compounds and processes | L'Oréal (FR) | 2007-02-28 | — | — | EP | claimed |
| EP-1738800-A1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer | L'Oréal (FR) | 2007-01-03 | — | — | EP | claimed |
| EP-1738801-A1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid | L'Oréal (FR) | 2007-01-03 | — | — | EP | claimed |
| EP-1430876-A1 | Composition containing a direct dyestuff and a specific polymer for colouring of keratinic fibres, method for the preparation thereof and process of dyeing with such a composition | L'OREAL (FR) | 2004-06-23 | — | — | EP | claimed |
| EP-0646108-B1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | OREAL (FR) | 1998-10-14 | — | — | EP | claimed |
| EP-0646109-B1 | NOVEL HYDROXYETHYLATED 2-NITRO-P-PHENYLENEDIAMINES AND USE THEREOF FOR DYEING KERATIN FIBRES | OREAL (FR) | 1997-09-03 | — | — | EP | claimed |
| EP-0673926-B1 | 2-Nitro-p-phenylenediamines having a sulfur atom in position 5, process for their preparation, dye compositions containing them and their use for dyeing keratinic fibres | OREAL (FR) | 1997-04-09 | — | — | EP | claimed |
| US-5516942-A | DIRECT DYES FOR HAIR FOR YELLOW OR PURPLE | L'OREAL (FR) | 1996-05-14 | — | — | US | claimed |
| EP-0673926-A1 | 2-Nitro-p-phenylenediamines having a sulfur atom in position 5, process for their preparation, dye compositions containing them and their use for dyeing keratinic fibres | L'OREAL (FR) | 1995-09-27 | — | — | EP | claimed |
| EP-0646108-A1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1995-04-05 | — | — | EP | claimed |
| WO-1994000414-A1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1994-01-06 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110020251-A1 | Ultraviolet-Absorbing Compounds | UFM1, UHRF1, CUTA | MAPT 322/4885TDP1 2312/4885KMT2A 756/4885 |
| US-20070044251-A1 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | KRT18, DSG1, PLOD2 | MAPT 645/4885TDP1 1969/4885KMT2A 1664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.