SCHEMBL22927394

SCHEMBL22927394

c1ccc(-c2nc3ccccc3nc2-n2c3ccccc3c3c4cccc5c4c(cc32)-c2ccncc2-c2ccccc2-5)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.33
CASP1 P29466 2/20 0.33
CYP1A2 P05177 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
HIF1A Q16665 1/20 0.33
TOP2A P11388 1/20 0.33
CYP17A1 P05093 1/20 0.33
TNF P01375 1/20 0.33
HRH4 Q9H3N8 1/20 0.33
DHODH Q02127 3/20 0.32
RAD51 Q06609 2/20 0.32
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
LCK P06239 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22927341 0.92 ALDH1A1 (0.39) HSD17B10CASP1CYP1A2ALDH1A1HPGD
SCHEMBL22927379 0.86 TNF (0.34) HSD17B10CASP1CYP1A2ALDH1A1HPGD
SCHEMBL22927329 0.86 TNF (0.34) HSD17B10CASP1CYP1A2ALDH1A1HPGD
SCHEMBL22927390 0.86 ALDH1A1 (0.39) HSD17B10CASP1CYP1A2ALDH1A1HPGD
SCHEMBL22927372 0.83 MAPT (0.34) HSD17B10CASP1CYP1A2ALDH1A1HPGD
SCHEMBL22927316 0.82 TNF (0.34) HSD17B10CASP1CYP1A2ALDH1A1HPGD
SCHEMBL22927363 0.81 CYP17A1 (0.35) HSD17B10CASP1CYP1A2ALDH1A1HPGD
SCHEMBL24037046 0.80 HSD17B10 (0.41) HSD17B10CASP1ALDH1A1HPGDL3MBTL1
SCHEMBL22927348 0.80 TNF (0.34) HSD17B10CASP1CYP1A2ALDH1A1HPGD
SCHEMBL22927347 0.80 TNF (0.34) HSD17B10CASP1CYP1A2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210024466-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210024466-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ICOSLG, SOD1, OR10J3 HSD17B10 2926/4885CASP1 714/4885CYP1A2 2615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.