Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3651436 | 1.00 | HTR3A (0.52) | HTR3AHTR2CTP53RECQLHTR1A | |
| SCHEMBL29580849 | 1.00 | HTR3A (0.52) | HTR3AHTR2CTP53RECQLHTR1A | |
| Hydrochloric Acid SCHEMBL4572974 | 0.98 | HTR3A (0.50) | HTR3AHTR2CTP53RECQLHTR1A | |
| Oxalic Acid SCHEMBL3546962 | 0.90 | JAK3 (0.47) | HTR3ATP53RECQLSLC6A2SLC6A4 | |
| SCHEMBL3697519 | 0.89 | HTR2A (0.51) | HTR3AHTR2CTP53RECQLSLC6A2 | |
| SCHEMBL3962252 | 0.88 | HTR2C (0.60) | HTR2CTP53RECQLHTR1ASLC6A2 | |
| Hydrochloric Acid SCHEMBL2884606 | 0.87 | HTR2A (0.50) | HTR3AHTR2CTP53RECQLSLC6A2 | |
| Hydrochloric Acid SCHEMBL1765134 | 0.86 | HTR2C (0.61) | HTR2CTP53RECQLHTR1ASLC6A2 | |
| Hydrochloric Acid SCHEMBL30952434 | 0.86 | HTR2C (0.61) | HTR2CTP53RECQLHTR1ASLC6A2 | |
| SCHEMBL1822134 | 0.85 | HTR3A (0.49) | HTR3AHTR2CHTR1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210024498-A1 | TETRAHYDROPYRROLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | MEDICONNS SHANGHAI BIOPHARMACEUTICAL CO LTD (CN) | 2021-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210024498-A1 | TETRAHYDROPYRROLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | PRLHR, DRD2, AVPR2 | HTR3A 123/4885HTR2C 25/4885TP53 2875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.