Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17775052 | 0.88 | MEN1 (0.40) | MEN1KMT2ALMNAALDH1A1ALOX15 | |
| SCHEMBL12238630 | 0.81 | MEN1 (0.36) | MEN1KMT2ALMNAALDH1A1ALOX15 | |
| SCHEMBL4989751 | 0.80 | CA1 (0.35) | MEN1KMT2ALMNASMN1; SMN2POLB | |
| SCHEMBL22928449 | 0.79 | MAOA (0.35) | MEN1KMT2ALMNASMN1; SMN2POLB | |
| SCHEMBL19448778 | 0.79 | CYP3A4 (0.39) | MEN1KMT2ALMNASMN1; SMN2POLB | |
| SCHEMBL18905278 | 0.79 | MEN1 (0.34) | MEN1KMT2ALMNACYP2D6CYP2C9 | |
| SCHEMBL12238616 | 0.79 | TSHR (0.50) | MEN1KMT2ALMNAALDH1A1HTT | |
| SCHEMBL19130232 | 0.79 | TSHR (0.50) | MEN1KMT2ALMNAALDH1A1HTT | |
| SCHEMBL706386 | 0.77 | APP (0.35) | MEN1KMT2ALMNACYP2D6CYP2C9 | |
| SCHEMBL12238642 | 0.77 | KMT2A (0.60) | MEN1KMT2ALMNASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3380101-B1 | EIF4-A-INHIBITING COMPOUNDS AND METHODS RELATED THERETO | EFFECTOR THERAPEUTICS INC (US) | 2021-01-27 | — | — | EP | disclosed |