Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2294862 | 1.00 | CYP2C9 (0.40) | CYP2C9CYP2C19ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL2297261 | 0.91 | USP30 (0.39) | ALDH1A1ENPP3ENPP1ENPP2 | |
| SCHEMBL2298269 | 0.91 | USP30 (0.39) | ALDH1A1ENPP3ENPP1ENPP2 | |
| SCHEMBL2293182 | 0.88 | ENPP3 (0.44) | CYP2C9CYP2C19ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL2294412 | 0.88 | ENPP3 (0.44) | CYP2C9CYP2C19ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL2296164 | 0.87 | KMT2A (0.44) | CYP2C9CYP2C19ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL2295739 | 0.87 | KMT2A (0.44) | CYP2C9CYP2C19ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL3374352 | 0.86 | ALDH1A1 (0.43) | CYP2C9CYP2C19ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL3372092 | 0.86 | ALDH1A1 (0.43) | CYP2C9CYP2C19ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL2297496 | 0.86 | MOGAT2 (0.37) | ALDH1A1ENPP3ENPP1SMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110257392-A1 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF | SANOFI-AVENTIS (FR) | 2011-10-20 | — | — | US | disclosed |
| US-20110251385-A1 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF | SANOFI-AVENTIS (FR) | 2011-10-13 | — | — | US | disclosed |
| US-7994315-B2 | Intermediate compound for synthesizing pharmaceutical agent and production method thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257392-A1 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF | MAPT, PSEN1, PSEN2 | CYP2C9 1988/4885CYP2C19 1737/4885ALDH1A1 1251/4885 |
| US-20110251385-A1 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF | MAPT, PSEN1, PSEN2 | CYP2C9 1988/4885CYP2C19 1737/4885ALDH1A1 1251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.