Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4132243 | 0.75 | RIPK1 (0.49) | RIPK1BRD4KMT2AALDH1A1TSHR | |
| SCHEMBL11133372 | 0.75 | RIPK1 (0.45) | RIPK1BRD4KMT2AALDH1A1TSHR | |
| SCHEMBL11133370 | 0.75 | RIPK1 (0.45) | RIPK1BRD4KMT2AALDH1A1TSHR | |
| SCHEMBL12620555 | 0.75 | RIPK1 (0.56) | RIPK1BRD4KMT2AALDH1A1TSHR | |
| SCHEMBL523273 | 0.73 | ESR1 (0.62) | RIPK1BRD4KMT2AALDH1A1TSHR | |
| SCHEMBL24775446 | 0.71 | RIPK1 (0.55) | RIPK1BRD4KMT2AALDH1A1TSHR | |
| SCHEMBL1827356 | 0.71 | RIPK1 (0.45) | RIPK1BRD4KMT2AALDH1A1TSHR | |
| SCHEMBL30054156 | 0.71 | RIPK1 (0.53) | RIPK1BRD4KMT2AALDH1A1TSHR | |
| SCHEMBL17870940 | 0.71 | RIPK1 (0.53) | RIPK1BRD4KMT2AALDH1A1TSHR | |
| SCHEMBL17870941 | 0.71 | RIPK1 (0.53) | RIPK1BRD4KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10906913-B2 | NMDA receptor modulators and uses thereof | NORTHWESTERN UNIVERSITY (US) | 2021-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10906913-B2 | NMDA receptor modulators and uses thereof | GRIN1, GRIN2A, GRIN3A | RIPK1 1059/4885PKM 1023/4885BRD4 2815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.