Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.69 |
| ▸ | RARG | P13631 | 9/20 | 0.69 |
| ▸ | RARA | P10276 | 7/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | PGR | P06401 | 1/20 | 0.69 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.69 |
| ▸ | GOT1 | P17174 | 1/20 | 0.69 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30015507 | 1.00 | RARB (0.69) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL20025499 | 0.94 | RARB (0.62) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL8766163 | 0.90 | RARG (0.74) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL31020222 | 0.89 | HDAC11 (0.67) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL8766420 | 0.88 | RARB (0.76) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL22929252 | 0.85 | RARB (0.51) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL5081246 | 0.84 | RARB (0.74) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL163779 | 0.83 | RARG (0.70) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL8767123 | 0.83 | RARG (0.70) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL30153290 | 0.83 | RARG (0.70) | RARBRARGRARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11819484-B2 | Retinoid derivatives with antitumor activity | BIOGEM S.C. A R.L. (IT) | 2023-11-21 | — | — | US | disclosed |
| US-11819484-B2 | Retinoid derivatives with antitumor activity | BIOGEM S.C. A R.L. (IT) | 2023-11-21 | — | — | US | disclosed |
| CN-110114338-B | Retinoid derivatives having antitumor activity | 比奥吉公司 | 2022-10-21 | — | — | CN | disclosed |
| US-11364216-B2 | Retinoid derivatives with antitumor activity | BIOGEM S.C. A R.L. (IT) | 2022-06-21 | — | — | US | disclosed |
| US-20220168252-A1 | RETINOID DERIVATIVES WITH ANTITUMOR ACTIVITY | BIOGEM S C A R L (IT) | 2022-06-02 | — | — | US | disclosed |
| US-20210052530-A1 | RETINOID DERIVATIVES WITH ANTITUMOR ACTIVITY | BIOGEM S C A R L (IT) | 2021-02-25 | — | — | US | disclosed |
| US-10905668-B2 | Retinoid derivatives with antitumor activity | BIOGEM S.C. A R.L. (IT) | 2021-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220168252-A1 | RETINOID DERIVATIVES WITH ANTITUMOR ACTIVITY | RARA, RARB, RARG | RARB 2/4885RARG 3/4885RARA 1/4885 |
| US-10905668-B2 | Retinoid derivatives with antitumor activity | RARA, RARB, RARG | RARB 2/4885RARG 3/4885RARA 1/4885 |
| US-11819484-B2 | Retinoid derivatives with antitumor activity | RARA, RARB, RARG | RARB 2/4885RARG 3/4885RARA 1/4885 |
| US-20210052530-A1 | RETINOID DERIVATIVES WITH ANTITUMOR ACTIVITY | RARA, RARB, RARG | RARB 2/4885RARG 3/4885RARA 1/4885 |
| US-11364216-B2 | Retinoid derivatives with antitumor activity | RARA, RARB, RARG | RARB 2/4885RARG 3/4885RARA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.